Role of HEG1 and Claudin-4 Immunohistochemistry in the Differential Diagnosis of Lung Adenocarcinoma from Malignant Mesothelioma in Pleural Effusion Cytology

Role of HEG1 and Claudin-4 Immunohistochemistry in the Differential Diagnosis of Lung Adenocarcinoma from Malignant Mesothelioma in Pleural Effusion Cytology

Objective: Cytological examination of pleural effusion is minimally invasive and low risk but faces challenges due to the lack of architectural features, low cell counts, and overlapping characteristics among reactive mesothelial cells (RMCs), carcinoma cells, and malignant epithelioid mesothelioma...

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Bibliographic Details
Main Authors: Aziza E. ABDELRAHMAN, Fatma A. ELBADRY, Taiseer R. IBRAHIM, Mohamed Ali ALABIAD, Mohamed AWAD
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2025-05-01
Series:Türk Patoloji Dergisi
Subjects:
heg1
claudin-4
malignant mesothelioma
lung adenocarcinoma
pleural effusion
Online Access:https://turkjpath.org/pdf.php?id=2085
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