CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS
Total lung capacity (TLC), lung capacity (LC), forced LC (FLC), intrathoracic volume (ITV), pulmonary residual volume (PRV), forced expiratory volume in one second (FEV1 ), (FEV1 )/LC%, peak expiratory flow (PEF), maximum expiratory flow rate (MEFR)25, MEFR50, MEFR75, Raw, Rin, Rex, DLCO-SB, DLCO-SB...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2014-10-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/291 |
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| author | V. B. Nefedov L. A. Popova E. A. Shergina N. N. Makaryants |
| author_facet | V. B. Nefedov L. A. Popova E. A. Shergina N. N. Makaryants |
| author_sort | V. B. Nefedov |
| collection | DOAJ |
| description | Total lung capacity (TLC), lung capacity (LC), forced LC (FLC), intrathoracic volume (ITV), pulmonary residual volume (PRV), forced expiratory volume in one second (FEV1 ), (FEV1 )/LC%, peak expiratory flow (PEF), maximum expiratory flow rate (MEFR)25, MEFR50, MEFR75, Raw, Rin, Rex, DLCO-SB, DLCO-SB/VА, РаО2 , and РаСО2 were determined in 43 patients with exogenous allergic alveolitis (EAA) before, during, and after treatment with glucocorticosteroids, hemapheresis, ambroxol, and fluimucil. Lung function became better in more than half (53.5%) of the patients and worse in one fourth (25.6%); a combination of positive and negative functional changes was detected in 14.0%. Improved lung function was noted in 75.0, 50.0, and 38.5% of the patients with acute, subacute, and chronic EAA, respectively. Deterioration of lung function was determined in 46.2, 22.2, and 8.3% of the patients with chronic, subacute, and acute alveolitis, respectively. Better lung function manifested itself mainly as positive changes in lung volumes and capacities and pulmonary gas exchange function, less frequently as improved bronchial patency in the patients with acute and subacute EAA whereas the rate of positive functional changes in lung volumes and capacities, bronchial patency, and pulmonary gas exchange function was equal in those with chronic EAA. Poorer lung function appeared as negative changes in lung volumes and capacities in the patients with acute EAA, as worse pulmonary gas exchange function and negative changes in lung volumes and capacities and deteriorated bronchial patency in those with subacute and chronic EAA. |
| format | Article |
| id | doaj-art-0f03c80d23c349a284713ddcc64cd5b1 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2014-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-0f03c80d23c349a284713ddcc64cd5b12025-08-20T01:47:33ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-10-01010434910.21292/2075-1230-2014-0-10-43-49291CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITISV. B. Nefedov0L. A. Popova1E. A. Shergina2N. N. Makaryants3ФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваTotal lung capacity (TLC), lung capacity (LC), forced LC (FLC), intrathoracic volume (ITV), pulmonary residual volume (PRV), forced expiratory volume in one second (FEV1 ), (FEV1 )/LC%, peak expiratory flow (PEF), maximum expiratory flow rate (MEFR)25, MEFR50, MEFR75, Raw, Rin, Rex, DLCO-SB, DLCO-SB/VА, РаО2 , and РаСО2 were determined in 43 patients with exogenous allergic alveolitis (EAA) before, during, and after treatment with glucocorticosteroids, hemapheresis, ambroxol, and fluimucil. Lung function became better in more than half (53.5%) of the patients and worse in one fourth (25.6%); a combination of positive and negative functional changes was detected in 14.0%. Improved lung function was noted in 75.0, 50.0, and 38.5% of the patients with acute, subacute, and chronic EAA, respectively. Deterioration of lung function was determined in 46.2, 22.2, and 8.3% of the patients with chronic, subacute, and acute alveolitis, respectively. Better lung function manifested itself mainly as positive changes in lung volumes and capacities and pulmonary gas exchange function, less frequently as improved bronchial patency in the patients with acute and subacute EAA whereas the rate of positive functional changes in lung volumes and capacities, bronchial patency, and pulmonary gas exchange function was equal in those with chronic EAA. Poorer lung function appeared as negative changes in lung volumes and capacities in the patients with acute EAA, as worse pulmonary gas exchange function and negative changes in lung volumes and capacities and deteriorated bronchial patency in those with subacute and chronic EAA.https://www.tibl-journal.com/jour/article/view/291lung functionexogenous allergic alveolitis |
| spellingShingle | V. B. Nefedov L. A. Popova E. A. Shergina N. N. Makaryants CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS Туберкулез и болезни лёгких lung function exogenous allergic alveolitis |
| title | CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS |
| title_full | CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS |
| title_fullStr | CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS |
| title_full_unstemmed | CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS |
| title_short | CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS |
| title_sort | changes in lung function in the treatment of patients with exogenous allergic alveolitis |
| topic | lung function exogenous allergic alveolitis |
| url | https://www.tibl-journal.com/jour/article/view/291 |
| work_keys_str_mv | AT vbnefedov changesinlungfunctioninthetreatmentofpatientswithexogenousallergicalveolitis AT lapopova changesinlungfunctioninthetreatmentofpatientswithexogenousallergicalveolitis AT eashergina changesinlungfunctioninthetreatmentofpatientswithexogenousallergicalveolitis AT nnmakaryants changesinlungfunctioninthetreatmentofpatientswithexogenousallergicalveolitis |