Astragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction

Astragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction

Abstract Acute myocardial infarction (AMI) is a threat to health, with high morbidity and mortality, posing a challenge to the public health system. This study aimed to explore the efficacy and potential targets of Astragaloside IV (AS-IV) combined with Mesenchymal Stem Cells (MSC)-derived exosomes...

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Bibliographic Details
Main Authors: Sha Zhongxin, Chen Zhijie, Du Feng, Guo Mei Qin, Zhong Ya, Hu Jinxin, Wei Zhang, Yu Zhenqiu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Astragaloside IV
Myocardial infarction
Mesenchymal stem cells
Exosome
PDHA1
Online Access:https://doi.org/10.1038/s41598-025-08628-5
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