High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients

Peripheral artery disease (PAD), traditionally affecting older adults, is increasingly diagnosed in younger patients, highlighting the need for early, non-invasive biomarkers such as the leukocyte glycemic index (LGI) that reflect the inflammatory mechanisms driving atherosclerosis. The aim of this...

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Main Authors: Coșarcă Mircea Cătălin, Horváth Emőke, Lazăr Nicolae-Alexandru, Carașcă Cosmin, Ráduly Gergő, Constantin Maria, Szanto Ludovic-Alexandru, Bandici Corneliu Bogdan, Bartus Réka, Șincaru Suzana-Vasilica, Mureșan Adrian Vasile
Format: Article
Language:English
Published: Sciendo 2025-07-01
Series:Journal of Cardiovascular Emergencies
Subjects:
Online Access:https://doi.org/10.2478/jce-2025-0006
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author Coșarcă Mircea Cătălin
Horváth Emőke
Lazăr Nicolae-Alexandru
Carașcă Cosmin
Ráduly Gergő
Constantin Maria
Szanto Ludovic-Alexandru
Bandici Corneliu Bogdan
Bartus Réka
Șincaru Suzana-Vasilica
Mureșan Adrian Vasile
author_facet Coșarcă Mircea Cătălin
Horváth Emőke
Lazăr Nicolae-Alexandru
Carașcă Cosmin
Ráduly Gergő
Constantin Maria
Szanto Ludovic-Alexandru
Bandici Corneliu Bogdan
Bartus Réka
Șincaru Suzana-Vasilica
Mureșan Adrian Vasile
author_sort Coșarcă Mircea Cătălin
collection DOAJ
description Peripheral artery disease (PAD), traditionally affecting older adults, is increasingly diagnosed in younger patients, highlighting the need for early, non-invasive biomarkers such as the leukocyte glycemic index (LGI) that reflect the inflammatory mechanisms driving atherosclerosis. The aim of this study was to determine whether the LGI can be associated with the presence of symptomatic atherosclerotic disease on patients under 45 years.
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issn 2457-5518
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publishDate 2025-07-01
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series Journal of Cardiovascular Emergencies
spelling doaj-art-0ef86d6d4cd14c48af943b2e20c65cdd2025-08-20T02:42:48ZengSciendoJournal of Cardiovascular Emergencies2457-55182025-07-01112546010.2478/jce-2025-0006High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young PatientsCoșarcă Mircea Cătălin0Horváth Emőke1Lazăr Nicolae-Alexandru2Carașcă Cosmin3Ráduly Gergő4Constantin Maria5Szanto Ludovic-Alexandru6Bandici Corneliu Bogdan7Bartus Réka8Șincaru Suzana-Vasilica9Mureșan Adrian Vasile10Department of Anatomy and Embryology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Pathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaDepartment of Forensic Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Anatomy and Embryology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaFaculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology,Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaClinic of Vascular Surgery, Emergency County Hospital Targu Mures,Târgu Mureș, RomaniaPeripheral artery disease (PAD), traditionally affecting older adults, is increasingly diagnosed in younger patients, highlighting the need for early, non-invasive biomarkers such as the leukocyte glycemic index (LGI) that reflect the inflammatory mechanisms driving atherosclerosis. The aim of this study was to determine whether the LGI can be associated with the presence of symptomatic atherosclerotic disease on patients under 45 years.https://doi.org/10.2478/jce-2025-0006leukocyte glycemic indexperipheral arterial diseasevascular surgeryyoung arteriopathyinflammatory biomarkers
spellingShingle Coșarcă Mircea Cătălin
Horváth Emőke
Lazăr Nicolae-Alexandru
Carașcă Cosmin
Ráduly Gergő
Constantin Maria
Szanto Ludovic-Alexandru
Bandici Corneliu Bogdan
Bartus Réka
Șincaru Suzana-Vasilica
Mureșan Adrian Vasile
High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
Journal of Cardiovascular Emergencies
leukocyte glycemic index
peripheral arterial disease
vascular surgery
young arteriopathy
inflammatory biomarkers
title High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
title_full High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
title_fullStr High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
title_full_unstemmed High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
title_short High Values of the Leukocyte Glycemic Index Are Associated with Symptomatic Systemic Atherosclerotic Disease in Young Patients
title_sort high values of the leukocyte glycemic index are associated with symptomatic systemic atherosclerotic disease in young patients
topic leukocyte glycemic index
peripheral arterial disease
vascular surgery
young arteriopathy
inflammatory biomarkers
url https://doi.org/10.2478/jce-2025-0006
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