Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)

Study of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is demonstrated. However, content of the B-lymphoc...

Full description

Saved in:
Bibliographic Details
Main Authors: V. V. Voytkova, V. I. Dubrovina, S. V. Lukyanov, O. V. Yuryeva, O. B. Kol’Esnikova, K. M. Korytov, G. P. Aleksandrova, V. P. Iljin, S. V. Balakhonov
Format: Article
Language:Russian
Published: Numikom LLC 2015-04-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/48
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849411608659361792
author V. V. Voytkova
V. I. Dubrovina
S. V. Lukyanov
O. V. Yuryeva
O. B. Kol’Esnikova
K. M. Korytov
G. P. Aleksandrova
V. P. Iljin
S. V. Balakhonov
author_facet V. V. Voytkova
V. I. Dubrovina
S. V. Lukyanov
O. V. Yuryeva
O. B. Kol’Esnikova
K. M. Korytov
G. P. Aleksandrova
V. P. Iljin
S. V. Balakhonov
author_sort V. V. Voytkova
collection DOAJ
description Study of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is demonstrated. However, content of the B-lymphocyte circulating subpopulations depends on the time of observation. Co-AG exhibits adjuvant properties enhanced the immunogenic features of the S-2 B. anthracis 34F2 Sterne that may indicate its availability as an adjuvant in the construction of chemical vaccines.
format Article
id doaj-art-0ef508299c754d6fbda96911d342a8d3
institution Kabale University
issn 2073-3046
2619-0494
language Russian
publishDate 2015-04-01
publisher Numikom LLC
record_format Article
series Эпидемиология и вакцинопрофилактика
spelling doaj-art-0ef508299c754d6fbda96911d342a8d32025-08-20T03:34:44ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942015-04-0114210711210.31631/2073-3046-2015-14-2-107-11247Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)V. V. Voytkova0V. I. Dubrovina1S. V. Lukyanov2O. V. Yuryeva3O. B. Kol’Esnikova4K. M. Korytov5G. P. Aleksandrova6V. P. Iljin7S. V. Balakhonov8Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Institute of Chemistry named of A.E. Favorsky of the Siberian Branch of Russian Academy of SciencesIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceIrkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human Well-Being SurveillanceStudy of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is demonstrated. However, content of the B-lymphocyte circulating subpopulations depends on the time of observation. Co-AG exhibits adjuvant properties enhanced the immunogenic features of the S-2 B. anthracis 34F2 Sterne that may indicate its availability as an adjuvant in the construction of chemical vaccines.https://www.epidemvac.ru/jour/article/view/48сибирская язваантигенынанокомпозитыиммунитетв-лимфоцитыanthraxantigenbloodnanocompositeimmunityb-lymphocytes
spellingShingle V. V. Voytkova
V. I. Dubrovina
S. V. Lukyanov
O. V. Yuryeva
O. B. Kol’Esnikova
K. M. Korytov
G. P. Aleksandrova
V. P. Iljin
S. V. Balakhonov
Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
Эпидемиология и вакцинопрофилактика
сибирская язва
антигены
нанокомпозиты
иммунитет
в-лимфоциты
anthrax
antigen
blood
nanocomposite
immunity
b-lymphocytes
title Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
title_full Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
title_fullStr Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
title_full_unstemmed Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
title_short Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
title_sort influence of bacillus anthracis 34f sub 2 sub sterne antigen preparations in combination with cobaltarabinogalactan on the subpopulation structure of b lymphocytes communication 2
topic сибирская язва
антигены
нанокомпозиты
иммунитет
в-лимфоциты
anthrax
antigen
blood
nanocomposite
immunity
b-lymphocytes
url https://www.epidemvac.ru/jour/article/view/48
work_keys_str_mv AT vvvoytkova influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT vidubrovina influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT svlukyanov influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT ovyuryeva influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT obkolesnikova influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT kmkorytov influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT gpaleksandrova influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT vpiljin influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2
AT svbalakhonov influenceofbacillusanthracis34fsub2substerneantigenpreparationsincombinationwithcobaltarabinogalactanonthesubpopulationstructureofblymphocytescommunication2