Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports

Patients with systemic lupus erythematosus (SLE) typically have an increased risk of thrombosis, especially at a younger age. The prognosis of those acute ischemic stroke (AIS) patients due to acute intracranial artery occlusion seems to be favorable; however, with few published reports. We report t...

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Main Authors: Weilong Hua, Lijun Wang, Hongye Xu, Hongyu Ma, Yongxin Zhang, Hongjian Shen, Xiaoxi Zhang, Pengfei Xing, Pengfei Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Future Science OA
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Online Access:https://www.tandfonline.com/doi/10.1080/20565623.2025.2534329
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author Weilong Hua
Lijun Wang
Hongye Xu
Hongyu Ma
Yongxin Zhang
Hongjian Shen
Xiaoxi Zhang
Pengfei Xing
Pengfei Yang
author_facet Weilong Hua
Lijun Wang
Hongye Xu
Hongyu Ma
Yongxin Zhang
Hongjian Shen
Xiaoxi Zhang
Pengfei Xing
Pengfei Yang
author_sort Weilong Hua
collection DOAJ
description Patients with systemic lupus erythematosus (SLE) typically have an increased risk of thrombosis, especially at a younger age. The prognosis of those acute ischemic stroke (AIS) patients due to acute intracranial artery occlusion seems to be favorable; however, with few published reports. We report two cases of AIS that were treated with intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) with a prior diagnosis of SLE and were treated with regular oral corticosteroids before the onset. During the 1-year follow-up, these two patients were able to live normally without experiencing another ischemic stroke or changing medication. SLE-associated strokes necessitate urgent attention, with prompt diagnosis and immediate therapeutic measures, including thrombolytic therapy or MT, being crucial for achieving favorable patient outcomes.
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publisher Taylor & Francis Group
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spelling doaj-art-0ef0a698317e4cd184239ac746d95db22025-08-20T02:41:00ZengTaylor & Francis GroupFuture Science OA2056-56232025-12-0111110.1080/20565623.2025.2534329Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reportsWeilong Hua0Lijun Wang1Hongye Xu2Hongyu Ma3Yongxin Zhang4Hongjian Shen5Xiaoxi Zhang6Pengfei Xing7Pengfei Yang8Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, ChinaPatients with systemic lupus erythematosus (SLE) typically have an increased risk of thrombosis, especially at a younger age. The prognosis of those acute ischemic stroke (AIS) patients due to acute intracranial artery occlusion seems to be favorable; however, with few published reports. We report two cases of AIS that were treated with intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) with a prior diagnosis of SLE and were treated with regular oral corticosteroids before the onset. During the 1-year follow-up, these two patients were able to live normally without experiencing another ischemic stroke or changing medication. SLE-associated strokes necessitate urgent attention, with prompt diagnosis and immediate therapeutic measures, including thrombolytic therapy or MT, being crucial for achieving favorable patient outcomes.https://www.tandfonline.com/doi/10.1080/20565623.2025.2534329Acute ischemic strokeintracranial artery occlusionintravenous thrombolysismechanical thrombectomysystemic lupus erythematosus
spellingShingle Weilong Hua
Lijun Wang
Hongye Xu
Hongyu Ma
Yongxin Zhang
Hongjian Shen
Xiaoxi Zhang
Pengfei Xing
Pengfei Yang
Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
Future Science OA
Acute ischemic stroke
intracranial artery occlusion
intravenous thrombolysis
mechanical thrombectomy
systemic lupus erythematosus
title Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
title_full Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
title_fullStr Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
title_full_unstemmed Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
title_short Endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus: two case reports
title_sort endovascular thrombectomy of acute ischemic stroke patients with systemic lupus erythematosus two case reports
topic Acute ischemic stroke
intracranial artery occlusion
intravenous thrombolysis
mechanical thrombectomy
systemic lupus erythematosus
url https://www.tandfonline.com/doi/10.1080/20565623.2025.2534329
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