A Comparative Analysis of the Gut Microbiota in Patients With Parkinson’s Disease Worldwide: A Systematic Review

Conclusions: There were no consistent patterns in the changes in α- and β-diversities of the gut microbiota among PD worldwide. Across all continents, there was an increase in Proteobacteria and Lactobacillaceae and a decrease in Lachnospiraceae and Roseburia. Despite these similar trends, there wer...

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Main Authors: Mira Beisembayeva, Yelena Shayakhmetova, Shynar Muratbekova, Irina Li, Eduard Yakupov, Rauan Kaiyrzhanov, Marina Grigolashvili
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Clinical Practice
Online Access:http://dx.doi.org/10.1155/ijcp/5511146
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Summary:Conclusions: There were no consistent patterns in the changes in α- and β-diversities of the gut microbiota among PD worldwide. Across all continents, there was an increase in Proteobacteria and Lactobacillaceae and a decrease in Lachnospiraceae and Roseburia. Despite these similar trends, there were also differences that may be attributed to factors such as ethnic background, geography, and dietary habits. These differences suggest that individualized approaches to treatment may be necessary to effectively manage PD-related gastrointestinal symptoms.
ISSN:1742-1241