Infusion Therapy Optimization in Selective Abdominal Surgery
Purpose. Evaluation of the influence of intra-operative targeted infusion therapy managed by the monitoring of stroke volume variability on post-operative results of major surgeries of gastrointestinal organs.Materials and Methods. The prospective study included 80 patients subjected to selective op...
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2018-10-01
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| Series: | Общая реаниматология |
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| Online Access: | https://www.reanimatology.com/rmt/article/view/1708 |
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| author | I. A. Smeshnoi I. N. Pasechnik E. I. Skobelev D. A. Timashkov М. A. Onegin Yu. V. Nikiforov S. I. Kontarev |
| author_facet | I. A. Smeshnoi I. N. Pasechnik E. I. Skobelev D. A. Timashkov М. A. Onegin Yu. V. Nikiforov S. I. Kontarev |
| author_sort | I. A. Smeshnoi |
| collection | DOAJ |
| description | Purpose. Evaluation of the influence of intra-operative targeted infusion therapy managed by the monitoring of stroke volume variability on post-operative results of major surgeries of gastrointestinal organs.Materials and Methods. The prospective study included 80 patients subjected to selective operative interventions of abdominal organs involving entero-enteroanastomosis. In the experimental group (n=39), the infusion therapy was conducted according to the developed targeted therapy protocol, of which the key parameter was stroke volume variability. In the control group (n=41), infusion therapy was conducted based on routine hemodynamic monitoring (average arterial pressure, heart rate, blood loss level with regard to intra-operative situation). In both groups, operative intervention was carried out in identical conditions (combined anesthesia, identical drugs to induce and maintain anesthesia); the only differences included infusion therapy.Results. In the experimental group versus the control group the intra-operative infusion volume was smaller, the number of patients with complications and the total number of complications were reliably lower, and the gastrointestinal tract functional recovery occurred earlier. Conclusion. A targeted infusion therapy based on a stroke volume variability monitoring as the key parameter allows optimizing the infusion load and facilitates reduction of the number of patients with complications and earlier recovery of gastrointestinal tract functions after major operative abdominal interventions. |
| format | Article |
| id | doaj-art-0ee6195b0af54dd2b77cbf3c9cb12a78 |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2018-10-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-0ee6195b0af54dd2b77cbf3c9cb12a782025-08-20T03:35:07ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102018-10-0114541510.15360/1813-9779-2018-5-4-151652Infusion Therapy Optimization in Selective Abdominal SurgeryI. A. Smeshnoi0I. N. Pasechnik1E. I. Skobelev2D. A. Timashkov3М. A. Onegin4Yu. V. Nikiforov5S. I. Kontarev6The Central State Medical Academy; Clinical HospitalThe Central State Medical Academy; Clinical HospitalThe Central State Medical AcademyClinical HospitalClinical HospitalV. A. Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; City Clinical Hospital No. 51, Moscow City Healthcare DepartmentCity Clinical Hospital No. 51, Moscow City Healthcare DepartmentPurpose. Evaluation of the influence of intra-operative targeted infusion therapy managed by the monitoring of stroke volume variability on post-operative results of major surgeries of gastrointestinal organs.Materials and Methods. The prospective study included 80 patients subjected to selective operative interventions of abdominal organs involving entero-enteroanastomosis. In the experimental group (n=39), the infusion therapy was conducted according to the developed targeted therapy protocol, of which the key parameter was stroke volume variability. In the control group (n=41), infusion therapy was conducted based on routine hemodynamic monitoring (average arterial pressure, heart rate, blood loss level with regard to intra-operative situation). In both groups, operative intervention was carried out in identical conditions (combined anesthesia, identical drugs to induce and maintain anesthesia); the only differences included infusion therapy.Results. In the experimental group versus the control group the intra-operative infusion volume was smaller, the number of patients with complications and the total number of complications were reliably lower, and the gastrointestinal tract functional recovery occurred earlier. Conclusion. A targeted infusion therapy based on a stroke volume variability monitoring as the key parameter allows optimizing the infusion load and facilitates reduction of the number of patients with complications and earlier recovery of gastrointestinal tract functions after major operative abdominal interventions.https://www.reanimatology.com/rmt/article/view/1708targeted infusion therapystroke volume variability (svv)functional hemodynamic parametershypovolemiahypervolemiadelivery of oxygen |
| spellingShingle | I. A. Smeshnoi I. N. Pasechnik E. I. Skobelev D. A. Timashkov М. A. Onegin Yu. V. Nikiforov S. I. Kontarev Infusion Therapy Optimization in Selective Abdominal Surgery Общая реаниматология targeted infusion therapy stroke volume variability (svv) functional hemodynamic parameters hypovolemia hypervolemia delivery of oxygen |
| title | Infusion Therapy Optimization in Selective Abdominal Surgery |
| title_full | Infusion Therapy Optimization in Selective Abdominal Surgery |
| title_fullStr | Infusion Therapy Optimization in Selective Abdominal Surgery |
| title_full_unstemmed | Infusion Therapy Optimization in Selective Abdominal Surgery |
| title_short | Infusion Therapy Optimization in Selective Abdominal Surgery |
| title_sort | infusion therapy optimization in selective abdominal surgery |
| topic | targeted infusion therapy stroke volume variability (svv) functional hemodynamic parameters hypovolemia hypervolemia delivery of oxygen |
| url | https://www.reanimatology.com/rmt/article/view/1708 |
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