A dual program for CRP-mediated regulation in bacterial alarmone (p)ppGpp
ABSTRACT Gene expression and proper downstream cellular functions upon facing environmental shifts depend on the combined and cooperative regulation of genetic networks. Here, we identified cAMP receptor protein (CRP) as a master regulator of (p)ppGpp (guanosine tetra- and penta-phosphate) homeostas...
Saved in:
| Main Authors: | Li Zhao, Shi-Yu Zhou, Yu Fu, Jin-Long Shen, Bin-Cheng Yin, Di You, Bang-Ce Ye |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2024-11-01
|
| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.02430-24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
(p)ppGpp and DksA play a crucial role in reducing the efficacy of β-lactam antibiotics by modulating bacterial membrane permeability
by: Meenal Chawla, et al.
Published: (2025-04-01) -
Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response
by: René Lysdal Bærentsen, et al.
Published: (2019-07-01) -
Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity
by: Fukang She, et al.
Published: (2025-04-01) -
Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells
by: Han G Ngo, et al.
Published: (2025-07-01) -
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
by: Eloïse M. Paulet, et al.
Published: (2025-07-01)