Emergent mechanics of a networked multivalent protein condensate

Abstract Multivalent proteins can form membraneless condensates in cells by liquid-liquid phase separation, and significant efforts have been made to study their biochemical properties. Here, we demonstrate the emergent mechanics of a functional multivalent condensate reconstituted with six postsyna...

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Bibliographic Details
Main Authors: Zhitao Liao, Bowen Jia, Dongshi Guan, Xudong Chen, Mingjie Zhang, Penger Tong
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60345-9
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