Human calculus adhesive-induced periodontitis model recapitulating human periodontitis microbiota in rats

Human calculus adhesive-induced periodontitis model recapitulating human periodontitis microbiota in rats

Abstract Background Periodontitis is a chronic inflammatory condition characterized by oral dysbiosis. Current animal models of periodontitis using ligation and pathogen inoculation are time-consuming and do not reflect the chronic characteristics of human periodontitis. One of the significant diffe...

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Bibliographic Details
Main Authors: Yuan You, Hong-Ling Wu, Dan-Yan Chen, Si-Yi Yu, Yue Xu, Ying Tang, Hua-Ling Sun, Cui Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Periodontitis
Animal disease model
Dental adhesives
Microbiota
Online Access:https://doi.org/10.1186/s12903-025-06398-0
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