Separation of cell survival, growth, migration, and mesenchymal transdifferentiation effects of fibroblast secretome on tumor cells of head and neck squamous cell carcinoma

Separation of cell survival, growth, migration, and mesenchymal transdifferentiation effects of fibroblast secretome on tumor cells of head and neck squamous cell carcinoma

Fibroblasts play a central role in tumor invasion, recurrence, and metastasis in head and neck squamous cell carcinoma. The aim of this study was to investigate the influence of tumor cell self-produced factors and paracrine fibroblast–secreted factors in comparison to indirect co-culture on cancer...

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Bibliographic Details
Main Authors: Veronika Maria Metzler, Christian Pritz, Anna Riml, Angela Romani, Raphaela Tuertscher, Teresa Steinbichler, Daniel Dejaco, Herbert Riechelmann, József Dudás
Format: Article
Language:English
Published: SAGE Publishing 2017-11-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705507
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