Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells
The role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system. The interaction between immune cells and BMSCs is crucial to...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Oral and Maxillofacial Surgery
2024-04-01
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| Series: | Kouqiang hemian waike zazhi |
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| Online Access: | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.013 |
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| author | SHI Yan GUO Hao ZHENG Kaijuan YANG Zhenming QIANG Jinbiao SHI Ce |
| author_facet | SHI Yan GUO Hao ZHENG Kaijuan YANG Zhenming QIANG Jinbiao SHI Ce |
| author_sort | SHI Yan |
| collection | DOAJ |
| description | The role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system. The interaction between immune cells and BMSCs is crucial to promoting bone formation in the healing of bone defects. In recent years, it has been found that a variety of immune cells promote osteogenic differentiation of BMSCs through the release of cytokines and signals. It is beneficial to bone defect repair and bone regeneration, and becomes a new therapeutic target for bone defect repair. Therefore, this article reviews the research status of the osteogenic effect of immune cells on BMSCs and related mechanisms. |
| format | Article |
| id | doaj-art-0eb304d22c964ff0ae8662ad76c3a70d |
| institution | Kabale University |
| issn | 1005-4979 |
| language | zho |
| publishDate | 2024-04-01 |
| publisher | Editorial Office of Journal of Oral and Maxillofacial Surgery |
| record_format | Article |
| series | Kouqiang hemian waike zazhi |
| spelling | doaj-art-0eb304d22c964ff0ae8662ad76c3a70d2025-08-25T06:10:59ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-04-0134215015310.12439/kqhm.1005-4979.2024.02.013Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cellsSHI Yan0GUO Hao1ZHENG Kaijuan2YANG Zhenming3QIANG Jinbiao4SHI Ce5Department of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaDepartment of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaDepartment of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaDepartment of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaDepartment of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaDepartment of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, ChinaThe role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system. The interaction between immune cells and BMSCs is crucial to promoting bone formation in the healing of bone defects. In recent years, it has been found that a variety of immune cells promote osteogenic differentiation of BMSCs through the release of cytokines and signals. It is beneficial to bone defect repair and bone regeneration, and becomes a new therapeutic target for bone defect repair. Therefore, this article reviews the research status of the osteogenic effect of immune cells on BMSCs and related mechanisms.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.013bone marrow mesenchymal stem cellsimmune cellosteogenic differentiationbone defect repair and bone regeneration |
| spellingShingle | SHI Yan GUO Hao ZHENG Kaijuan YANG Zhenming QIANG Jinbiao SHI Ce Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells Kouqiang hemian waike zazhi bone marrow mesenchymal stem cells immune cell osteogenic differentiation bone defect repair and bone regeneration |
| title | Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| title_full | Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| title_fullStr | Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| title_full_unstemmed | Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| title_short | Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| title_sort | research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells |
| topic | bone marrow mesenchymal stem cells immune cell osteogenic differentiation bone defect repair and bone regeneration |
| url | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.013 |
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