Exploring potential diagnostic markers and therapeutic targets for type 2 diabetes mellitus with major depressive disorder through bioinformatics and in vivo experiments

Exploring potential diagnostic markers and therapeutic targets for type 2 diabetes mellitus with major depressive disorder through bioinformatics and in vivo experiments

Abstract Type 2 diabetes mellitus (T2DM) and Major depressive disorder (MDD) act as risk factors for each other, and the comorbidity of both significantly increases the all-cause mortality rate. Therefore, studying the diagnosis and treatment of diabetes with depression (DD) is of great significance...

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Bibliographic Details
Main Authors: Yikai Zhang, Linyue Wu, Chuanjie Zheng, Huihui Xu, Weiye Lin, Zheng Chen, Lingyong Cao, Yiqian Qu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Diabetes with depression
Major depressive disorder (MDD)
Type 2 diabetes mellitus
Machine learning
Bioinformatics analysis
Diagnosis learning
Online Access:https://doi.org/10.1038/s41598-025-01175-z
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