Current Trends of Nanobiosensors for Point-of-Care Diagnostics

In order to provide better-quality health care, it is very important that high standards of health care management are achieved by making timely decisions based on rapid diagnostics, smart data analysis, and informatics analysis. Point-of-care testing ensures fast detection of analytes near to the p...

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Main Authors: Naumih M. Noah, Peter M. Ndangili
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2019/2179718
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author Naumih M. Noah
Peter M. Ndangili
author_facet Naumih M. Noah
Peter M. Ndangili
author_sort Naumih M. Noah
collection DOAJ
description In order to provide better-quality health care, it is very important that high standards of health care management are achieved by making timely decisions based on rapid diagnostics, smart data analysis, and informatics analysis. Point-of-care testing ensures fast detection of analytes near to the patients facilitating a better disease diagnosis, monitoring, and management. It also enables quick medical decisions since the diseases can be diagnosed at an early stage which leads to improved health outcomes for the patients enabling them to start early treatment. In the recent past, various potential point-of-care devices have been developed and they are paving the way to next-generation point-of-care testing. Biosensors are very critical components of point-of-care devices since they are directly responsible for the bioanalytical performance of an essay. As such, they have been explored for their prospective point-of-care applications necessary for personalized health care management since they usually estimate the levels of biological markers or any chemical reaction by producing signals mainly associated with the concentration of an analyte and hence can detect disease causing markers such as body fluids. Their high selectivity and sensitivity have allowed for early diagnosis and management of targeted diseases; hence, facilitating timely therapy decisions and combination with nanotechnology can improve assessment of the disease onset and its progression and help to plan for treatment of many diseases. In this review, we explore how nanotechnology has been utilized in the development of nanosensors and the current trends of these nanosensors for point-of-care diagnosis of various diseases.
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spelling doaj-art-0eabd24823274e4caa423c6b6d4e608c2025-02-03T06:06:10ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732019-01-01201910.1155/2019/21797182179718Current Trends of Nanobiosensors for Point-of-Care DiagnosticsNaumih M. Noah0Peter M. Ndangili1School of Pharmacy and Health Sciences, United States International University-Africa, P.O. Box 14634-00800, Nairobi, KenyaDepartment of Chemical Science and Technology (DCST), Technical University of Kenya, P.O. Box 52428-00200, Nairobi, KenyaIn order to provide better-quality health care, it is very important that high standards of health care management are achieved by making timely decisions based on rapid diagnostics, smart data analysis, and informatics analysis. Point-of-care testing ensures fast detection of analytes near to the patients facilitating a better disease diagnosis, monitoring, and management. It also enables quick medical decisions since the diseases can be diagnosed at an early stage which leads to improved health outcomes for the patients enabling them to start early treatment. In the recent past, various potential point-of-care devices have been developed and they are paving the way to next-generation point-of-care testing. Biosensors are very critical components of point-of-care devices since they are directly responsible for the bioanalytical performance of an essay. As such, they have been explored for their prospective point-of-care applications necessary for personalized health care management since they usually estimate the levels of biological markers or any chemical reaction by producing signals mainly associated with the concentration of an analyte and hence can detect disease causing markers such as body fluids. Their high selectivity and sensitivity have allowed for early diagnosis and management of targeted diseases; hence, facilitating timely therapy decisions and combination with nanotechnology can improve assessment of the disease onset and its progression and help to plan for treatment of many diseases. In this review, we explore how nanotechnology has been utilized in the development of nanosensors and the current trends of these nanosensors for point-of-care diagnosis of various diseases.http://dx.doi.org/10.1155/2019/2179718
spellingShingle Naumih M. Noah
Peter M. Ndangili
Current Trends of Nanobiosensors for Point-of-Care Diagnostics
Journal of Analytical Methods in Chemistry
title Current Trends of Nanobiosensors for Point-of-Care Diagnostics
title_full Current Trends of Nanobiosensors for Point-of-Care Diagnostics
title_fullStr Current Trends of Nanobiosensors for Point-of-Care Diagnostics
title_full_unstemmed Current Trends of Nanobiosensors for Point-of-Care Diagnostics
title_short Current Trends of Nanobiosensors for Point-of-Care Diagnostics
title_sort current trends of nanobiosensors for point of care diagnostics
url http://dx.doi.org/10.1155/2019/2179718
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