Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy
Recent studies reported that cytoplasmic dsDNA-induced activation of cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) signaling has tremendous potential for antitumor immunity by inducing the production of type I Interferon (IFN), resulting in activation of both innate and adapt...
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| Main Authors: | Hao Chen, Yang Zhong, Rongjie Feng, Xingyu Zhu, Kang Xu, Mingjie Kuang, Wei Chong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Molecular Biosciences |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2025.1556736/full |
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