Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population

Endoscoric injection therapy was performed in 341 patients consecutively admitted with a bleeding peptic ulcer at high risk of further hemorrhage, assessed by the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Initial hemostasis was achieved in 111 of 11...

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Main Authors: Joaqulm Balanzó, Candid Villanueva, Jorge C Espinós, Sergio Sáinz, German Soriano, Dolors González, Xavier Rius, Jorge Puig La Calle, Francisco Vilardell
Format: Article
Language:English
Published: Wiley 1992-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1992/416485
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author Joaqulm Balanzó
Candid Villanueva
Jorge C Espinós
Sergio Sáinz
German Soriano
Dolors González
Xavier Rius
Jorge Puig La Calle
Francisco Vilardell
author_facet Joaqulm Balanzó
Candid Villanueva
Jorge C Espinós
Sergio Sáinz
German Soriano
Dolors González
Xavier Rius
Jorge Puig La Calle
Francisco Vilardell
author_sort Joaqulm Balanzó
collection DOAJ
description Endoscoric injection therapy was performed in 341 patients consecutively admitted with a bleeding peptic ulcer at high risk of further hemorrhage, assessed by the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Initial hemostasis was achieved in 111 of 119 actively bleeding patients (93%). Rebleeding ocurred in 75 cases (23%), at a mean interval of 53±52 h. A second emergency injection was a ttempted in 36 therapeutic failures, and was successful in 20 (55%). Emergency surgery was finally required in 52 patients (15%). Overall mortality was 4.9%. Major complications occurred in four patients (1.2%) (two perforations and two aspiration pneumonia); therefore, injection therapy is an effective and simple method for treating bleeding ulcers, achieving the initial control of hemorrhage in a majority of cases although the rate of further hemorrhage is not negligible and complications are not irrelevant.
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institution Kabale University
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language English
publishDate 1992-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-0ea3233cc4ce4f749a1c39b6939429682025-08-20T03:54:24ZengWileyCanadian Journal of Gastroenterology0835-79001992-01-016526526810.1155/1992/416485Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk PopulationJoaqulm Balanzó0Candid Villanueva1Jorge C Espinós2Sergio Sáinz3German Soriano4Dolors González5Xavier Rius6Jorge Puig La Calle7Francisco Vilardell8Department of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Gastroenterology and Division of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainEndoscoric injection therapy was performed in 341 patients consecutively admitted with a bleeding peptic ulcer at high risk of further hemorrhage, assessed by the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Initial hemostasis was achieved in 111 of 119 actively bleeding patients (93%). Rebleeding ocurred in 75 cases (23%), at a mean interval of 53±52 h. A second emergency injection was a ttempted in 36 therapeutic failures, and was successful in 20 (55%). Emergency surgery was finally required in 52 patients (15%). Overall mortality was 4.9%. Major complications occurred in four patients (1.2%) (two perforations and two aspiration pneumonia); therefore, injection therapy is an effective and simple method for treating bleeding ulcers, achieving the initial control of hemorrhage in a majority of cases although the rate of further hemorrhage is not negligible and complications are not irrelevant.http://dx.doi.org/10.1155/1992/416485
spellingShingle Joaqulm Balanzó
Candid Villanueva
Jorge C Espinós
Sergio Sáinz
German Soriano
Dolors González
Xavier Rius
Jorge Puig La Calle
Francisco Vilardell
Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
Canadian Journal of Gastroenterology
title Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
title_full Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
title_fullStr Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
title_full_unstemmed Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
title_short Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
title_sort endoscopic injection therapy in bleeding peptic ulcers low mortality in a high risk population
url http://dx.doi.org/10.1155/1992/416485
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