Contribution of Genetic Causes in Ear Vestibular Disorders
Purpose:Vestibular disorders such as deafness are associated with heterogeneous genetic patterns and multifactorial hereditary transmission methods. Improvement in the field of genetic sequencing has provided evidence of familial classification in vestibular disorders and is the beginning for reveal...
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| Format: | Article |
| Language: | English |
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Mashhad university of medical Sciences
2024-12-01
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| Series: | Journal of Paramedical Science and Rehabilitation |
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| Online Access: | https://jpsr.mums.ac.ir/article_25484_57918b43c970558da38b5c728862c615.pdf |
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| author | Y Lotfi M Shaabani A Navaei Lavasani |
| author_facet | Y Lotfi M Shaabani A Navaei Lavasani |
| author_sort | Y Lotfi |
| collection | DOAJ |
| description | Purpose:Vestibular disorders such as deafness are associated with heterogeneous genetic patterns and multifactorial hereditary transmission methods. Improvement in the field of genetic sequencing has provided evidence of familial classification in vestibular disorders and is the beginning for revealing the genetic causes and new treatment options, especially in Meniere’s disease and disorders associated with hearing loss. In this review, our aim is to present the recent findings in the field of effective genes in vestibular disorders and investigating the possible treatment of these disorders.Methods:In this review article, the words “genes and vestibular diseases” and genetic therapy had searched in ‘google scholar” and “science direct” and "PubMed" databases in the years 2000 to 2023.Results:After searching in Google Scholar, Science Direct and PubMed databases, new and related articles were collected and studied, and about 32 articles were used in this study.Conclusion:The application of molecular and gene therapy for the restoration and return of hearing and vestibular disorder is significant. The discovery of possible new treatments for the creation of new hair cells are important advances in science that will facilitate further studies towards biological treatment of inner ear diseases. |
| format | Article |
| id | doaj-art-0ea1aff0e4ce47a1b04158abe335be1b |
| institution | DOAJ |
| issn | 2322-5238 2345-2730 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Mashhad university of medical Sciences |
| record_format | Article |
| series | Journal of Paramedical Science and Rehabilitation |
| spelling | doaj-art-0ea1aff0e4ce47a1b04158abe335be1b2025-08-20T03:09:00ZengMashhad university of medical SciencesJournal of Paramedical Science and Rehabilitation2322-52382345-27302024-12-01134859710.22038/jpsr.2025.75350.255925484Contribution of Genetic Causes in Ear Vestibular DisordersY Lotfi0M Shaabani1A Navaei Lavasani2Department of Audiology, University of Rehabilitation Sciences and Social Health, Tehran, IranDepartment of Audiology, University of Rehabilitation Sciences and Social Health, Tehran, IranDepartment of Audiology, University of Rehabilitation Sciences and Social Health, Tehran, IranPurpose:Vestibular disorders such as deafness are associated with heterogeneous genetic patterns and multifactorial hereditary transmission methods. Improvement in the field of genetic sequencing has provided evidence of familial classification in vestibular disorders and is the beginning for revealing the genetic causes and new treatment options, especially in Meniere’s disease and disorders associated with hearing loss. In this review, our aim is to present the recent findings in the field of effective genes in vestibular disorders and investigating the possible treatment of these disorders.Methods:In this review article, the words “genes and vestibular diseases” and genetic therapy had searched in ‘google scholar” and “science direct” and "PubMed" databases in the years 2000 to 2023.Results:After searching in Google Scholar, Science Direct and PubMed databases, new and related articles were collected and studied, and about 32 articles were used in this study.Conclusion:The application of molecular and gene therapy for the restoration and return of hearing and vestibular disorder is significant. The discovery of possible new treatments for the creation of new hair cells are important advances in science that will facilitate further studies towards biological treatment of inner ear diseases.https://jpsr.mums.ac.ir/article_25484_57918b43c970558da38b5c728862c615.pdf"vestibular diseases""gene""mutation""genetic therapy" |
| spellingShingle | Y Lotfi M Shaabani A Navaei Lavasani Contribution of Genetic Causes in Ear Vestibular Disorders Journal of Paramedical Science and Rehabilitation "vestibular diseases" "gene" "mutation" "genetic therapy" |
| title | Contribution of Genetic Causes in Ear Vestibular Disorders |
| title_full | Contribution of Genetic Causes in Ear Vestibular Disorders |
| title_fullStr | Contribution of Genetic Causes in Ear Vestibular Disorders |
| title_full_unstemmed | Contribution of Genetic Causes in Ear Vestibular Disorders |
| title_short | Contribution of Genetic Causes in Ear Vestibular Disorders |
| title_sort | contribution of genetic causes in ear vestibular disorders |
| topic | "vestibular diseases" "gene" "mutation" "genetic therapy" |
| url | https://jpsr.mums.ac.ir/article_25484_57918b43c970558da38b5c728862c615.pdf |
| work_keys_str_mv | AT ylotfi contributionofgeneticcausesinearvestibulardisorders AT mshaabani contributionofgeneticcausesinearvestibulardisorders AT anavaeilavasani contributionofgeneticcausesinearvestibulardisorders |