Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging

The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The...

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Main Authors: Dominik Paul, Maxim Zaitsev, Laura Harsan, Anja Kurutsch, Daniel Nico Splitthoff, Franciszek Hennel, Morwan Choli, Dominik von Elverfeldt
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2009/946271
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author Dominik Paul
Maxim Zaitsev
Laura Harsan
Anja Kurutsch
Daniel Nico Splitthoff
Franciszek Hennel
Morwan Choli
Dominik von Elverfeldt
author_facet Dominik Paul
Maxim Zaitsev
Laura Harsan
Anja Kurutsch
Daniel Nico Splitthoff
Franciszek Hennel
Morwan Choli
Dominik von Elverfeldt
author_sort Dominik Paul
collection DOAJ
description The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The correction procedure was applied to phantom and in vivo imaging of mice and rats at 9.4T using different SE-EPI and DWI-EPI protocols. Results show the significant improvement in image quality for single- and multishot EPI. Using a reduced FOV in the PSF encoding direction clearly reduced the acquisition time for PSF data by an acceleration factor of 2 or 4, without affecting the correction quality.
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issn 1687-4188
1687-4196
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publishDate 2009-01-01
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series International Journal of Biomedical Imaging
spelling doaj-art-0e97c21195b04d359364cbae31fe2ef32025-08-20T02:01:40ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962009-01-01200910.1155/2009/946271946271Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal ImagingDominik Paul0Maxim Zaitsev1Laura Harsan2Anja Kurutsch3Daniel Nico Splitthoff4Franciszek Hennel5Morwan Choli6Dominik von Elverfeldt7Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, 79106 Freiburg, GermanyDepartment of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, 79106 Freiburg, GermanyDepartment of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, 79106 Freiburg, GermanyInstitute of Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg, 79104 Freiburg, GermanyDepartment of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, 79106 Freiburg, GermanyBruker Biospin, Ettlingen, GermanyResearch Center Magnetic Resonance Bavaria e.V (MRB), 97074 Würzburg, GermanyDepartment of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, 79106 Freiburg, GermanyThe purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The correction procedure was applied to phantom and in vivo imaging of mice and rats at 9.4T using different SE-EPI and DWI-EPI protocols. Results show the significant improvement in image quality for single- and multishot EPI. Using a reduced FOV in the PSF encoding direction clearly reduced the acquisition time for PSF data by an acceleration factor of 2 or 4, without affecting the correction quality.http://dx.doi.org/10.1155/2009/946271
spellingShingle Dominik Paul
Maxim Zaitsev
Laura Harsan
Anja Kurutsch
Daniel Nico Splitthoff
Franciszek Hennel
Morwan Choli
Dominik von Elverfeldt
Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
International Journal of Biomedical Imaging
title Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
title_full Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
title_fullStr Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
title_full_unstemmed Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
title_short Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging
title_sort implementation and application of psf based epi distortion correction to high field animal imaging
url http://dx.doi.org/10.1155/2009/946271
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