Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging

The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The...

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Bibliographic Details
Main Authors: Dominik Paul, Maxim Zaitsev, Laura Harsan, Anja Kurutsch, Daniel Nico Splitthoff, Franciszek Hennel, Morwan Choli, Dominik von Elverfeldt
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2009/946271
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Summary:The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The correction procedure was applied to phantom and in vivo imaging of mice and rats at 9.4T using different SE-EPI and DWI-EPI protocols. Results show the significant improvement in image quality for single- and multishot EPI. Using a reduced FOV in the PSF encoding direction clearly reduced the acquisition time for PSF data by an acceleration factor of 2 or 4, without affecting the correction quality.
ISSN:1687-4188
1687-4196