Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life
Aim: Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. Materials & methods...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-06-01
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| Series: | CNS Oncology |
| Subjects: | |
| Online Access: | https://www.futuremedicine.com/doi/10.2217/cns-2022-0002 |
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| _version_ | 1850152280756584448 |
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| author | Kathleen Van Dyk Lucy Wall Brandon F Heimberg Justin Choi Catalina Raymond Chencai Wang Albert Lai Timothy F Cloughesy Benjamin M Ellingson Phioanh Nghiemphu |
| author_facet | Kathleen Van Dyk Lucy Wall Brandon F Heimberg Justin Choi Catalina Raymond Chencai Wang Albert Lai Timothy F Cloughesy Benjamin M Ellingson Phioanh Nghiemphu |
| author_sort | Kathleen Van Dyk |
| collection | DOAJ |
| description | Aim: Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. Materials & methods: We examined neuropsychological, self-reported cognition, mood and QoL correlates of work and non-work-related daily functioning in 23 glioma survivors, and carried out linear models of the best predictors. Results & conclusion: A total of 13/23 participants were working at the time of enrollment. The best model for worse work-related functioning (R2 = .83) included worse self-reported cognitive function, depression, loneliness and brain tumor symptoms. The best model for worse non-work-related functioning (R2 = .61) included worse self-reported cognitive functioning, anxiety, sleep disturbance and physical functioning. Neuropsychological variables were not among the most highly correlated with function. Worse cognitive, particularly self-reported and psychosocial outcomes may compromise optimal functioning in glioma survivors. |
| format | Article |
| id | doaj-art-0e9587c1033d481e94ab4f4170ebea6e |
| institution | OA Journals |
| issn | 2045-0907 2045-0915 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | CNS Oncology |
| spelling | doaj-art-0e9587c1033d481e94ab4f4170ebea6e2025-08-20T02:26:02ZengTaylor & Francis GroupCNS Oncology2045-09072045-09152022-06-01110210.2217/cns-2022-0002Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of lifeKathleen Van Dyk0Lucy Wall1Brandon F Heimberg2Justin Choi3Catalina Raymond4Chencai Wang5Albert Lai6Timothy F Cloughesy7Benjamin M Ellingson8Phioanh Nghiemphu91Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA1Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA1Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA3Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA4UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision & Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA4UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision & Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA2Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA 90024, USA2Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA 90024, USA1Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA2Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA 90024, USAAim: Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. Materials & methods: We examined neuropsychological, self-reported cognition, mood and QoL correlates of work and non-work-related daily functioning in 23 glioma survivors, and carried out linear models of the best predictors. Results & conclusion: A total of 13/23 participants were working at the time of enrollment. The best model for worse work-related functioning (R2 = .83) included worse self-reported cognitive function, depression, loneliness and brain tumor symptoms. The best model for worse non-work-related functioning (R2 = .61) included worse self-reported cognitive functioning, anxiety, sleep disturbance and physical functioning. Neuropsychological variables were not among the most highly correlated with function. Worse cognitive, particularly self-reported and psychosocial outcomes may compromise optimal functioning in glioma survivors.https://www.futuremedicine.com/doi/10.2217/cns-2022-0002cancerdaily functioningemploymentfunctiongliomaquality of life |
| spellingShingle | Kathleen Van Dyk Lucy Wall Brandon F Heimberg Justin Choi Catalina Raymond Chencai Wang Albert Lai Timothy F Cloughesy Benjamin M Ellingson Phioanh Nghiemphu Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life CNS Oncology cancer daily functioning employment function glioma quality of life |
| title | Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life |
| title_full | Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life |
| title_fullStr | Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life |
| title_full_unstemmed | Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life |
| title_short | Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life |
| title_sort | daily functioning in glioma survivors associations with cognitive function psychological factors and quality of life |
| topic | cancer daily functioning employment function glioma quality of life |
| url | https://www.futuremedicine.com/doi/10.2217/cns-2022-0002 |
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