Antimicrobial efficacy of QMix on Enterococcus faecalis infected root canals: a systematic review of in vitro studies
ObjectivesThis study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against Enterococcus faecalis.Materials and MethodsThe research question was developed by using population, intervention, comparison, outcome, and study desi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Academy of Conservative Dentistry
2020-05-01
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| Series: | Restorative Dentistry & Endodontics |
| Subjects: | |
| Online Access: | http://rde.ac/upload/pdf/rde-45-e23.pdf |
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| Summary: | ObjectivesThis study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against Enterococcus faecalis.Materials and MethodsThe research question was developed by using population, intervention, comparison, outcome, and study design framework. The literature search was performed using 3 electronic databases: PubMed, Scopus, and EBSCOhost until October 2019. The additional hand search was performed from the reference list of the eligible studies. The risk of bias of the studies was independently appraised using the revised Cochrane Risk of Bias tool (RoB 2.0).ResultsFourteen studies were included in this systematic review. The overall risk of bias for the selected studies was moderate. QMix was found to have a higher antimicrobial activity compared to 2% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), mixture of tetracycline isonomer, an acid and a detergent (MTAD), 0.2% Cetrimide, SilverSol/H2O2, HYBENX, and grape seed extract (GSE). QMix had higher antibacterial efficacy compared to NaOCl, only when used for a longer time (10 minutes) and with higher volume (above 3 mL).ConclusionsQMix has higher antibacterial activity than 17% EDTA, 2% CHX, MTAD, 0.2% Cetrimide, SilverSol/H2O2, HYBENX, GSE and NaOCl with lower concentration. To improve the effectiveness, QMix is to use for a longer time and at a higher volume.Trial RegistrationPROSPERO International prospective register of systematic reviews Identifier: CRD42018096763 |
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| ISSN: | 2234-7658 2234-7666 |