The impact of dietary interventions on cardiometabolic health
Abstract Obesity and cardiometabolic diseases are leading causes of morbidity and mortality among adults worldwide. These conditions significantly contribute to and exacerbate other major causes of illness and death, including cancer, neurodegenerative diseases, and chronic kidney disease. The growi...
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| Format: | Article |
| Language: | English |
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BMC
2025-05-01
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| Series: | Cardiovascular Diabetology |
| Online Access: | https://doi.org/10.1186/s12933-025-02766-w |
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| author | Erind Gjermeni Raluca Fiebiger Linnaeus Bundalian Antje Garten Torsten Schöneberg Diana Le Duc Matthias Blüher |
| author_facet | Erind Gjermeni Raluca Fiebiger Linnaeus Bundalian Antje Garten Torsten Schöneberg Diana Le Duc Matthias Blüher |
| author_sort | Erind Gjermeni |
| collection | DOAJ |
| description | Abstract Obesity and cardiometabolic diseases are leading causes of morbidity and mortality among adults worldwide. These conditions significantly contribute to and exacerbate other major causes of illness and death, including cancer, neurodegenerative diseases, and chronic kidney disease. The growing burden of these diseases has increased the interest of modern medicine in understanding metabolic processes and health, with diet emerging as a pivotal modifiable factor, alongside physical inactivity and smoking. In this review, we discuss the pathophysiological and evolutionary foundations of metabolic processes that may link “unhealthy” nutrition to obesity and cardiometabolic diseases and review the current literature to assess the effects of various diet interventions and patterns on cardiometabolic parameters. Special emphasis is placed on summarizing the latest, albeit partially contradictory, evidence to offer balanced dietary recommendations with the ultimate aim to improve cardiometabolic health. |
| format | Article |
| id | doaj-art-0e85df80328e48fd846e6ba71c376a13 |
| institution | OA Journals |
| issn | 1475-2840 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Diabetology |
| spelling | doaj-art-0e85df80328e48fd846e6ba71c376a132025-08-20T01:59:56ZengBMCCardiovascular Diabetology1475-28402025-05-0124111710.1186/s12933-025-02766-wThe impact of dietary interventions on cardiometabolic healthErind Gjermeni0Raluca Fiebiger1Linnaeus Bundalian2Antje Garten3Torsten Schöneberg4Diana Le Duc5Matthias Blüher6Department of Cardiology, Median Center for Rehabilitation SchmannewitzDepartment of Cardiology, Median Center for Rehabilitation SchmannewitzInstitute of Human Genetics, University Medical Center LeipzigPediatric Research Center, University Hospital for Children and Adolescents, Leipzig UniversityRudolf Schönheimer Institute of Biochemistry, Molecular Biochemistry, Medical Faculty, University of LeipzigInstitute of Human Genetics, University Medical Center LeipzigHelmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital LeipzigAbstract Obesity and cardiometabolic diseases are leading causes of morbidity and mortality among adults worldwide. These conditions significantly contribute to and exacerbate other major causes of illness and death, including cancer, neurodegenerative diseases, and chronic kidney disease. The growing burden of these diseases has increased the interest of modern medicine in understanding metabolic processes and health, with diet emerging as a pivotal modifiable factor, alongside physical inactivity and smoking. In this review, we discuss the pathophysiological and evolutionary foundations of metabolic processes that may link “unhealthy” nutrition to obesity and cardiometabolic diseases and review the current literature to assess the effects of various diet interventions and patterns on cardiometabolic parameters. Special emphasis is placed on summarizing the latest, albeit partially contradictory, evidence to offer balanced dietary recommendations with the ultimate aim to improve cardiometabolic health.https://doi.org/10.1186/s12933-025-02766-w |
| spellingShingle | Erind Gjermeni Raluca Fiebiger Linnaeus Bundalian Antje Garten Torsten Schöneberg Diana Le Duc Matthias Blüher The impact of dietary interventions on cardiometabolic health Cardiovascular Diabetology |
| title | The impact of dietary interventions on cardiometabolic health |
| title_full | The impact of dietary interventions on cardiometabolic health |
| title_fullStr | The impact of dietary interventions on cardiometabolic health |
| title_full_unstemmed | The impact of dietary interventions on cardiometabolic health |
| title_short | The impact of dietary interventions on cardiometabolic health |
| title_sort | impact of dietary interventions on cardiometabolic health |
| url | https://doi.org/10.1186/s12933-025-02766-w |
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