Digital Twins of Biological Systems: A Narrative Review

The concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modelin...

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Main Authors: Ghufran A. Alsalloum, Nour M. Al Sawaftah, Kelly M. Percival, Ghaleb A. Husseini
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Open Journal of Engineering in Medicine and Biology
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10596666/
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author Ghufran A. Alsalloum
Nour M. Al Sawaftah
Kelly M. Percival
Ghaleb A. Husseini
author_facet Ghufran A. Alsalloum
Nour M. Al Sawaftah
Kelly M. Percival
Ghaleb A. Husseini
author_sort Ghufran A. Alsalloum
collection DOAJ
description The concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modeling, integrating diverse data sources to computationally model dynamic biological systems. This narrative review explores potential DT applications in medicine, from defining DTs and their history to constructing DTs, modeling biologically relevant systems, as well as discussing the benefits, risks, and challenges in their application. The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fields
format Article
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institution Kabale University
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publishDate 2024-01-01
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series IEEE Open Journal of Engineering in Medicine and Biology
spelling doaj-art-0e83723595ff4a0bb600dfbb2d3372992025-01-29T00:01:29ZengIEEEIEEE Open Journal of Engineering in Medicine and Biology2644-12762024-01-01567067710.1109/OJEMB.2024.342691610596666Digital Twins of Biological Systems: A Narrative ReviewGhufran A. Alsalloum0https://orcid.org/0000-0002-1610-9807Nour M. Al Sawaftah1Kelly M. Percival2Ghaleb A. Husseini3https://orcid.org/0000-0002-7244-3105Department of Biosciences and Bioengineering, College of Engineering, American University of Sharjah, Sharjah, UAEDepartment of Material Science and Engineering, College of Engineering, American University of Sharjah, Sharjah, UAEDepartment of Chemical and Biological Engineering, College of Engineering, American University of Sharjah, Sharjah, UAEDepartment of Chemical and Biological Engineering, College of Engineering, American University of Sharjah, Sharjah, UAEThe concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modeling, integrating diverse data sources to computationally model dynamic biological systems. This narrative review explores potential DT applications in medicine, from defining DTs and their history to constructing DTs, modeling biologically relevant systems, as well as discussing the benefits, risks, and challenges in their application. The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fieldshttps://ieeexplore.ieee.org/document/10596666/Biological system modelingdigital twinmedical technology
spellingShingle Ghufran A. Alsalloum
Nour M. Al Sawaftah
Kelly M. Percival
Ghaleb A. Husseini
Digital Twins of Biological Systems: A Narrative Review
IEEE Open Journal of Engineering in Medicine and Biology
Biological system modeling
digital twin
medical technology
title Digital Twins of Biological Systems: A Narrative Review
title_full Digital Twins of Biological Systems: A Narrative Review
title_fullStr Digital Twins of Biological Systems: A Narrative Review
title_full_unstemmed Digital Twins of Biological Systems: A Narrative Review
title_short Digital Twins of Biological Systems: A Narrative Review
title_sort digital twins of biological systems a narrative review
topic Biological system modeling
digital twin
medical technology
url https://ieeexplore.ieee.org/document/10596666/
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AT ghalebahusseini digitaltwinsofbiologicalsystemsanarrativereview