Joint analysis of whole-genome methylation and transcriptome in avian pullorum disease and validation of gene function

Joint analysis of whole-genome methylation and transcriptome in avian pullorum disease and validation of gene function

Abstract Pullorum disease caused by Salmonella pullorum can negatively affect growth and egg-laying performance, resulting in significant economic losses in poultry farming. In this study, spleen tissues from SP-infected chickens (group P) and SP-uninfected chickens (group N) were analyzed for funct...

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Bibliographic Details
Main Authors: Jiongwen Wu, Weiming Liang, Aijun Liu, Xiaomeng Wang, Zhexia Fan, Xuerong Ma, Shuya Chen, Cheng Fang, Xiquan Zhang, Qingbin Luo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Genomics
Subjects:
Pullorum disease
Salmonella pullorum
Whole-genome bisulfite sequencing
Transcriptomics
Immune regulation
Online Access:https://doi.org/10.1186/s12864-025-11821-5
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