Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes

Objective: To investigate the significance of short wavelength automated perimetry (SWAP) in detecting retinal functional impairment in early diabetic patients without retinopathy and with mild non-proliferative diabetic retinopathy (NPDR). Materials and Methods: This is a prospective, cross-secti...

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Main Authors: Nikki Doreen S. Angbue Te, MD, Pearl M. Tamesis-Villalon, MD, Joseph Anthony J. Tumbocon, MD, Kristine D. Corpus, MD, Romulo N. Aguilar, MD
Format: Article
Language:English
Published: Philippine Academy of Ophthalmology 2016-12-01
Series:Philippine Journal of Ophthalmology
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Online Access:https://paojournal.com/index.php/pjo/article/view/148
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author Nikki Doreen S. Angbue Te, MD
Pearl M. Tamesis-Villalon, MD
Joseph Anthony J. Tumbocon, MD
Kristine D. Corpus, MD
Romulo N. Aguilar, MD
author_facet Nikki Doreen S. Angbue Te, MD
Pearl M. Tamesis-Villalon, MD
Joseph Anthony J. Tumbocon, MD
Kristine D. Corpus, MD
Romulo N. Aguilar, MD
author_sort Nikki Doreen S. Angbue Te, MD
collection DOAJ
description Objective: To investigate the significance of short wavelength automated perimetry (SWAP) in detecting retinal functional impairment in early diabetic patients without retinopathy and with mild non-proliferative diabetic retinopathy (NPDR). Materials and Methods: This is a prospective, cross-sectional study of 37 eyes of early diabetics which were divided into 2 groups: no DR with 18 subjects and mild NPDR with 19. All subjects underwent HBA1C, SWAP, peripapillary RNFL thickness measurement and fundus photo. Visual field indices: MD and PSD as well as average RNFL thickness were compared among the 2 groups. Correlation of MD with RNFL thickness and HBA1C were also analyzed. Results: There was no statistically significant difference in the MD (-4.46 ± 3.03 vs -2.94 ± 2.21; p=0.09), PSD (3.08 ± 1.28 vs 2.69 ± 0.47; p=0.23) and average peripapillary RNFL thickness (98.47 ± 6.89 vs 98.72 ± 11.01; p=0.93) among early diabetics with mild NPDR and no signs of DR. There is no correlation between MD and RNFL thickness in the no DR group (R2 =0.017) and the mild DR group (R2 =0.000). There was a weak correlation between MD and HBA1C in the no DR group (R2 =0.137), while no correlation was seen in the mild NPDR group (R2 =0.000). Conclusion: SWAP does not appear to be a sensitive measure of worsening retinopathy in older individuals with early diabetes. The usefulness of SWAP and peripapillary RNFL thickness in the early stages of retinopathy are inconclusive.
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spelling doaj-art-0e78d52cf04d4f2485e752e790d3d56f2025-08-20T02:41:18ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592016-12-014123238148Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early DiabetesNikki Doreen S. Angbue Te, MD0Pearl M. Tamesis-Villalon, MD1Joseph Anthony J. Tumbocon, MD2Kristine D. Corpus, MD3Romulo N. Aguilar, MD4International Eye Institute, St. Luke’s Medical Center 279 E. Rodriguez Sr. Blvd., Quezon City, 1102, PhilippinesInternational Eye Institute, St. Luke’s Medical Center 279 E. Rodriguez Sr. Blvd., Quezon City, 1102, PhilippinesInternational Eye Institute, St. Luke’s Medical Center 279 E. Rodriguez Sr. Blvd., Quezon City, 1102, PhilippinesInternational Eye Institute, St. Luke’s Medical Center 279 E. Rodriguez Sr. Blvd., Quezon City, 1102, PhilippinesInternational Eye Institute, St. Luke’s Medical Center 279 E. Rodriguez Sr. Blvd., Quezon City, 1102, PhilippinesObjective: To investigate the significance of short wavelength automated perimetry (SWAP) in detecting retinal functional impairment in early diabetic patients without retinopathy and with mild non-proliferative diabetic retinopathy (NPDR). Materials and Methods: This is a prospective, cross-sectional study of 37 eyes of early diabetics which were divided into 2 groups: no DR with 18 subjects and mild NPDR with 19. All subjects underwent HBA1C, SWAP, peripapillary RNFL thickness measurement and fundus photo. Visual field indices: MD and PSD as well as average RNFL thickness were compared among the 2 groups. Correlation of MD with RNFL thickness and HBA1C were also analyzed. Results: There was no statistically significant difference in the MD (-4.46 ± 3.03 vs -2.94 ± 2.21; p=0.09), PSD (3.08 ± 1.28 vs 2.69 ± 0.47; p=0.23) and average peripapillary RNFL thickness (98.47 ± 6.89 vs 98.72 ± 11.01; p=0.93) among early diabetics with mild NPDR and no signs of DR. There is no correlation between MD and RNFL thickness in the no DR group (R2 =0.017) and the mild DR group (R2 =0.000). There was a weak correlation between MD and HBA1C in the no DR group (R2 =0.137), while no correlation was seen in the mild NPDR group (R2 =0.000). Conclusion: SWAP does not appear to be a sensitive measure of worsening retinopathy in older individuals with early diabetes. The usefulness of SWAP and peripapillary RNFL thickness in the early stages of retinopathy are inconclusive.https://paojournal.com/index.php/pjo/article/view/148swapperimetryrnfldiabetesretinopathysensitivity
spellingShingle Nikki Doreen S. Angbue Te, MD
Pearl M. Tamesis-Villalon, MD
Joseph Anthony J. Tumbocon, MD
Kristine D. Corpus, MD
Romulo N. Aguilar, MD
Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
Philippine Journal of Ophthalmology
swap
perimetry
rnfl
diabetes
retinopathy
sensitivity
title Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
title_full Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
title_fullStr Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
title_full_unstemmed Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
title_short Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes
title_sort short wavelength automated perimetry and peripapillary retinal nerve fiber layer in early diabetes
topic swap
perimetry
rnfl
diabetes
retinopathy
sensitivity
url https://paojournal.com/index.php/pjo/article/view/148
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