Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review)
Aim. To review the main indications for probiotics prescription in patients with irritable bowel syndrome and to present the materials of an Expert Council, which was held on 18 March 2022 in Moscow.Key points. Gut microbiota disturbance is an integral part of irritable bowel syndrome (IBS) pathogen...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2022-08-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/696 |
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| author | V. T. Ivashkin I. V. Maev O. P. Alekseeva S. A. Alekseenko N. V. Korochanskaya E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov O. S. Shifrin T. L. Lapina R. V. Maslennikov A. I. Ulyanin |
| author_facet | V. T. Ivashkin I. V. Maev O. P. Alekseeva S. A. Alekseenko N. V. Korochanskaya E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov O. S. Shifrin T. L. Lapina R. V. Maslennikov A. I. Ulyanin |
| author_sort | V. T. Ivashkin |
| collection | DOAJ |
| description | Aim. To review the main indications for probiotics prescription in patients with irritable bowel syndrome and to present the materials of an Expert Council, which was held on 18 March 2022 in Moscow.Key points. Gut microbiota disturbance is an integral part of irritable bowel syndrome (IBS) pathogenesis. Changes of colonic microbiota composition are associated with its functional potential modification, which leads to an increasing of the pro-inflammatory immune response, as well as to an exacerbation of the disease symptoms and quality of life decreasing in patients with IBS. The novel coronavirus infection (COVID-19) is an independent risk factor for both exacerbation and onset of IBS, which predispose to increase IBS incidence. Correction of gut microbiota composition with probiotics seems to be a promising therapeutic target for IBS treatment optimizing. The optimal probiotic should be effective, safe, strain-specific, and its dose and duration of administration should be confirmed by the results of clinical studies. Some of the probiotics with proven efficacy in IBS are Alflorex® and Enterol®.Conclusion. Prescription of certain probiotics in IBS is advisable to normalize the frequency and consistency of stools, relieve abdominal pain and bloating, as well as improve patients’ quality of life. |
| format | Article |
| id | doaj-art-0e761013bbe5499bac02bdc38639ed8c |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2022-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-0e761013bbe5499bac02bdc38639ed8c2025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732022-08-0132291810.22416/1382-4376-2022-32-2-9-18468Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review)V. T. Ivashkin0I. V. Maev1O. P. Alekseeva2S. A. Alekseenko3N. V. Korochanskaya4E. A. Poluektova5V. I. Simanenkov6A. S. Trukhmanov7I. B. Khlynov8V. V. Tsukanov9O. S. Shifrin10T. L. Lapina11R. V. Maslennikov12A. I. Ulyanin13Sechenov First Moscow State Medical University (Sechenov University)A.I. Yevdokimov Moscow State University of Medicine and DentistryPrivolzhsky Research Medical UniversityFar-Eastern State Medical UniversityKuban State Medical UniversitySechenov First Moscow State Medical University (Sechenov University)I.I. Mechnikov North-West State Medical UniversitySechenov First Moscow State Medical University (Sechenov University)Ural State Medical UniversityResearch Institute for Medical Problems in the North — Division of Krasnoyarsk Scientific Centre of the Siberian Branch of the RASSechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Aim. To review the main indications for probiotics prescription in patients with irritable bowel syndrome and to present the materials of an Expert Council, which was held on 18 March 2022 in Moscow.Key points. Gut microbiota disturbance is an integral part of irritable bowel syndrome (IBS) pathogenesis. Changes of colonic microbiota composition are associated with its functional potential modification, which leads to an increasing of the pro-inflammatory immune response, as well as to an exacerbation of the disease symptoms and quality of life decreasing in patients with IBS. The novel coronavirus infection (COVID-19) is an independent risk factor for both exacerbation and onset of IBS, which predispose to increase IBS incidence. Correction of gut microbiota composition with probiotics seems to be a promising therapeutic target for IBS treatment optimizing. The optimal probiotic should be effective, safe, strain-specific, and its dose and duration of administration should be confirmed by the results of clinical studies. Some of the probiotics with proven efficacy in IBS are Alflorex® and Enterol®.Conclusion. Prescription of certain probiotics in IBS is advisable to normalize the frequency and consistency of stools, relieve abdominal pain and bloating, as well as improve patients’ quality of life.https://www.gastro-j.ru/jour/article/view/696irritable bowel syndromenovel coronavirus infectioncovid-19probioticsbifidobacterium longum 35624alflorex®saccharomyces boulardii cncm i-745enterol® |
| spellingShingle | V. T. Ivashkin I. V. Maev O. P. Alekseeva S. A. Alekseenko N. V. Korochanskaya E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov O. S. Shifrin T. L. Lapina R. V. Maslennikov A. I. Ulyanin Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) Российский журнал гастроэнтерологии, гепатологии, колопроктологии irritable bowel syndrome novel coronavirus infection covid-19 probiotics bifidobacterium longum 35624 alflorex® saccharomyces boulardii cncm i-745 enterol® |
| title | Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) |
| title_full | Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) |
| title_fullStr | Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) |
| title_full_unstemmed | Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) |
| title_short | Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) |
| title_sort | determination of probiotics prescription indications in patients with irritable bowel syndrome materials of the expert council and literature review |
| topic | irritable bowel syndrome novel coronavirus infection covid-19 probiotics bifidobacterium longum 35624 alflorex® saccharomyces boulardii cncm i-745 enterol® |
| url | https://www.gastro-j.ru/jour/article/view/696 |
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