Toxicological effect of olaquindox on liver cells and pancreas exocrine cells of Ctenopharyngodon idellus
Olaquindox has the toxic function of cumulation, heredity and seduction. This research used Hepato-pancreas of Ctenopharyngodon idellus as experimental material to study toxicological effect of olaquindox on liver cell and pancreas exocrine cell of Ctenopharyngodon idellus, using the method of histo...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zhejiang University Press
2006-11-01
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| Series: | 浙江大学学报. 农业与生命科学版 |
| Subjects: | |
| Online Access: | https://www.academax.com/doi/10.3785/1008-9209.2006.06.0651 |
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| Summary: | Olaquindox has the toxic function of cumulation, heredity and seduction. This research used Hepato-pancreas of Ctenopharyngodon idellus as experimental material to study toxicological effect of olaquindox on liver cell and pancreas exocrine cell of Ctenopharyngodon idellus, using the method of histochemistry, primary cell culture, and immunocytochemistry, and the cells were observed by TEM and LSCM. The result indicated when the concentration of olaquindox was higher than 0.30 μg·mL<sup>-1</sup>, it could increase the depot fat of liver cell and pancreas exocrine cell of Ctenopharyngodon idellus, and interdict the biosynthysis of trypsinogen of pancreas exocrine cell. In 1.8 μg·mL<sup>-1</sup> olaquindox experimental group, some cellular cross section of pancreas exocrine cells of Ctenopharyngodon idellus was metamorphosed into pathological polygon. |
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| ISSN: | 1008-9209 2097-5155 |