Secreted phosphoprotein 1 on ophthalmic diseases
Secreted phosphoprotein 1 (SPP1) , a multifunctional phosphorylated glycoprotein, has recently emerged as a research focus due to its pivotal regulatory role in ophthalmic diseases. Through diverse molecular mechanisms including modulation of apoptotic pathways, regulation of oxidative stress respon...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
The Editorial Department of Chinese Journal of Clinical Research
2025-05-01
|
| Series: | Zhongguo linchuang yanjiu |
| Subjects: | |
| Online Access: | http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20250530 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849729581983989760 |
|---|---|
| author | LIU Yuan SANG Aimin |
| author_facet | LIU Yuan SANG Aimin |
| author_sort | LIU Yuan |
| collection | DOAJ |
| description | Secreted phosphoprotein 1 (SPP1) , a multifunctional phosphorylated glycoprotein, has recently emerged as a research focus due to its pivotal regulatory role in ophthalmic diseases. Through diverse molecular mechanisms including modulation of apoptotic pathways, regulation of oxidative stress responses, and mediation of inflammatory processes, SPP1 is intricately involved in the pathogenesis and progression of various ocular disorders such as dry eye syndrome, glaucoma, and diabetic retinopathy. These finding sunder score the significant role of SPP1 in ophthalmic diseases. This review aims to systematically summarize the latest advances in SPP1research within the field of ophthalmology, with the goal of providing novel theoretical foundations and therapeutic strategies for the prevention and treatment of ocular diseases through in.depth analysis of SPP1..s molecular mechanisms. |
| format | Article |
| id | doaj-art-0e702c1dbeb042cdb1c5bb37069ac128 |
| institution | DOAJ |
| issn | 1674-8182 |
| language | zho |
| publishDate | 2025-05-01 |
| publisher | The Editorial Department of Chinese Journal of Clinical Research |
| record_format | Article |
| series | Zhongguo linchuang yanjiu |
| spelling | doaj-art-0e702c1dbeb042cdb1c5bb37069ac1282025-08-20T03:09:11ZzhoThe Editorial Department of Chinese Journal of Clinical ResearchZhongguo linchuang yanjiu1674-81822025-05-0138579780110.13429/j.cnki.cjcr.2025.05.030Secreted phosphoprotein 1 on ophthalmic diseasesLIU Yuan0SANG Aimin1Medical School of Nantong University, Nantong, Jiangsu 226001, China; Ophthalmology Department of Nantong University Affiliated Hospital, Nantong, Jiangsu 226001, ChinaMedical School of Nantong University, Nantong, Jiangsu 226001, China; Ophthalmology Department of Nantong University Affiliated Hospital, Nantong, Jiangsu 226001, ChinaSecreted phosphoprotein 1 (SPP1) , a multifunctional phosphorylated glycoprotein, has recently emerged as a research focus due to its pivotal regulatory role in ophthalmic diseases. Through diverse molecular mechanisms including modulation of apoptotic pathways, regulation of oxidative stress responses, and mediation of inflammatory processes, SPP1 is intricately involved in the pathogenesis and progression of various ocular disorders such as dry eye syndrome, glaucoma, and diabetic retinopathy. These finding sunder score the significant role of SPP1 in ophthalmic diseases. This review aims to systematically summarize the latest advances in SPP1research within the field of ophthalmology, with the goal of providing novel theoretical foundations and therapeutic strategies for the prevention and treatment of ocular diseases through in.depth analysis of SPP1..s molecular mechanisms. http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20250530secreted phosphoprotein 1retinal diseasesuveal diseasesocular diseasesglaucomapterygiumxerophthalmiamelanoma |
| spellingShingle | LIU Yuan SANG Aimin Secreted phosphoprotein 1 on ophthalmic diseases Zhongguo linchuang yanjiu secreted phosphoprotein 1 retinal diseases uveal diseases ocular diseases glaucoma pterygium xerophthalmia melanoma |
| title | Secreted phosphoprotein 1 on ophthalmic diseases |
| title_full | Secreted phosphoprotein 1 on ophthalmic diseases |
| title_fullStr | Secreted phosphoprotein 1 on ophthalmic diseases |
| title_full_unstemmed | Secreted phosphoprotein 1 on ophthalmic diseases |
| title_short | Secreted phosphoprotein 1 on ophthalmic diseases |
| title_sort | secreted phosphoprotein 1 on ophthalmic diseases |
| topic | secreted phosphoprotein 1 retinal diseases uveal diseases ocular diseases glaucoma pterygium xerophthalmia melanoma |
| url | http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20250530 |
| work_keys_str_mv | AT liuyuan secretedphosphoprotein1onophthalmicdiseases AT sangaimin secretedphosphoprotein1onophthalmicdiseases |