Treatment of patients with prolonged course of medial temporal epilepsy
Objective. The aim of the study was to evaluate the efficacy of treatment in patients with prolonged duration of medial temporal epilepsy (MTE).Materials and methods. We studied cases of 93 patients with history of MTE lasted more than 10 years.Results. This form of epilepsy is often characterized b...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2018-11-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/424 |
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| _version_ | 1850048046562279424 |
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| author | V. E. Kitaeva A. S. Kotov |
| author_facet | V. E. Kitaeva A. S. Kotov |
| author_sort | V. E. Kitaeva |
| collection | DOAJ |
| description | Objective. The aim of the study was to evaluate the efficacy of treatment in patients with prolonged duration of medial temporal epilepsy (MTE).Materials and methods. We studied cases of 93 patients with history of MTE lasted more than 10 years.Results. This form of epilepsy is often characterized by drug resistance; therefore, patients have to try different medications before the effective one is found (in 12% of cases, patients tried 5-7 different medicines). Nevertheless, in 48.4% of patients, pharmacotherapy is ineffective. According to our findings, patients with an early MTE debut and those with an epileptogenic focus (by EEG / MRI data) in the medial temporal zone are most likely to have treatment-resistant epilepsy.Conclusion. If the therapy is ineffective, patients should be referred to preoperational examination. |
| format | Article |
| id | doaj-art-0e6c8a6384a24ae18c3b567bf197d3f2 |
| institution | DOAJ |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2018-11-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-0e6c8a6384a24ae18c3b567bf197d3f22025-08-20T02:54:04ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882018-11-01103313710.17749/2077-8333.2018.10.3.031-037407Treatment of patients with prolonged course of medial temporal epilepsyV. E. Kitaeva0A. S. Kotov1A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of the Russian FederationMoscow Regional Research and Clinical InstituteObjective. The aim of the study was to evaluate the efficacy of treatment in patients with prolonged duration of medial temporal epilepsy (MTE).Materials and methods. We studied cases of 93 patients with history of MTE lasted more than 10 years.Results. This form of epilepsy is often characterized by drug resistance; therefore, patients have to try different medications before the effective one is found (in 12% of cases, patients tried 5-7 different medicines). Nevertheless, in 48.4% of patients, pharmacotherapy is ineffective. According to our findings, patients with an early MTE debut and those with an epileptogenic focus (by EEG / MRI data) in the medial temporal zone are most likely to have treatment-resistant epilepsy.Conclusion. If the therapy is ineffective, patients should be referred to preoperational examination.https://www.epilepsia.su/jour/article/view/424medial temporal epilepsydrug resistancefebrile seizureshippocampal sclerosiscompliance |
| spellingShingle | V. E. Kitaeva A. S. Kotov Treatment of patients with prolonged course of medial temporal epilepsy Эпилепсия и пароксизмальные состояния medial temporal epilepsy drug resistance febrile seizures hippocampal sclerosis compliance |
| title | Treatment of patients with prolonged course of medial temporal epilepsy |
| title_full | Treatment of patients with prolonged course of medial temporal epilepsy |
| title_fullStr | Treatment of patients with prolonged course of medial temporal epilepsy |
| title_full_unstemmed | Treatment of patients with prolonged course of medial temporal epilepsy |
| title_short | Treatment of patients with prolonged course of medial temporal epilepsy |
| title_sort | treatment of patients with prolonged course of medial temporal epilepsy |
| topic | medial temporal epilepsy drug resistance febrile seizures hippocampal sclerosis compliance |
| url | https://www.epilepsia.su/jour/article/view/424 |
| work_keys_str_mv | AT vekitaeva treatmentofpatientswithprolongedcourseofmedialtemporalepilepsy AT askotov treatmentofpatientswithprolongedcourseofmedialtemporalepilepsy |