ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS
H^t of occurrence of sheep and goat pox and peste des petits rum^nts requires development of new vaccines and improvement of available associated ones. Their administration allows for the reduction of vaccination time frames and cost. The study results demonstrated tat associated as well as monovale...
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| Format: | Article |
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Da Vinci Media
2018-04-01
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| Series: | Ветеринария сегодня |
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| Online Access: | https://veterinary.arriah.ru/jour/article/view/316 |
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| author | A. V. Konstantinov S. K. Starov V. I. Diev N. V. Moroz E. V. Kurnenkova D. K. Basova A. V. Kononov K. Yu. Fedoseyev V. P. Melnikov |
| author_facet | A. V. Konstantinov S. K. Starov V. I. Diev N. V. Moroz E. V. Kurnenkova D. K. Basova A. V. Kononov K. Yu. Fedoseyev V. P. Melnikov |
| author_sort | A. V. Konstantinov |
| collection | DOAJ |
| description | H^t of occurrence of sheep and goat pox and peste des petits rum^nts requires development of new vaccines and improvement of available associated ones. Their administration allows for the reduction of vaccination time frames and cost. The study results demonstrated tat associated as well as monovalent virus vaccines against sheep pox, goat pox and peste des petits rum^nts have good antigenic properties. The vaccination induced high level of virus neutralizing antibodies against each of the above listed diseases and ensured formation of strong immunity tat is supported by the results of tallenge of sheep with virulent sheep pox virus (“Afghanistan” strain). In 14 and 21 days in blood of sheep immunized with the virus vaccine against sheep pox, goat pox and peste des petits rum^nts titres of antibodies against sheep pox virus ((4.17±0.12)-(4.84±0.31)) and PPR ((5.92±0.23)-(6.08±0.23)) were higher as compared to goat pox antibody titres ((1.99±0.89)-(3.53±0.58) log2). Herewith, antibody titres in blood sera of animals vaccinated with monovalent vaccine against sheep pox were higher against homologous virus ((3.62±0.12)- (4.08±0.31)) as compared to goat pox ((2.50±0.50)-(2.25±0.25) log2). The data demonstrate tat the associated vaccines may be used for preventive vaccination against sheep pox, goat pox and peste des petits rum^nts. |
| format | Article |
| id | doaj-art-0e401f80ae8646a899ce8e2b0dd3ad46 |
| institution | Kabale University |
| issn | 2304-196X 2658-6959 |
| language | English |
| publishDate | 2018-04-01 |
| publisher | Da Vinci Media |
| record_format | Article |
| series | Ветеринария сегодня |
| spelling | doaj-art-0e401f80ae8646a899ce8e2b0dd3ad462025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-04-01032832316ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTSA. V. Konstantinov0S. K. Starov1V. I. Diev2N. V. Moroz3E. V. Kurnenkova4D. K. Basova5A. V. Kononov6K. Yu. Fedoseyev7V. P. Melnikov8FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirH^t of occurrence of sheep and goat pox and peste des petits rum^nts requires development of new vaccines and improvement of available associated ones. Their administration allows for the reduction of vaccination time frames and cost. The study results demonstrated tat associated as well as monovalent virus vaccines against sheep pox, goat pox and peste des petits rum^nts have good antigenic properties. The vaccination induced high level of virus neutralizing antibodies against each of the above listed diseases and ensured formation of strong immunity tat is supported by the results of tallenge of sheep with virulent sheep pox virus (“Afghanistan” strain). In 14 and 21 days in blood of sheep immunized with the virus vaccine against sheep pox, goat pox and peste des petits rum^nts titres of antibodies against sheep pox virus ((4.17±0.12)-(4.84±0.31)) and PPR ((5.92±0.23)-(6.08±0.23)) were higher as compared to goat pox antibody titres ((1.99±0.89)-(3.53±0.58) log2). Herewith, antibody titres in blood sera of animals vaccinated with monovalent vaccine against sheep pox were higher against homologous virus ((3.62±0.12)- (4.08±0.31)) as compared to goat pox ((2.50±0.50)-(2.25±0.25) log2). The data demonstrate tat the associated vaccines may be used for preventive vaccination against sheep pox, goat pox and peste des petits rum^nts.https://veterinary.arriah.ru/jour/article/view/316оспа овецоспа козчума мелких жвачныховцыкозывируснейтрализующие антителавирусвакцинасыворотка кровииммунитетsheep poxgoat poxpeste des petits rum^ntssheepgoatsvirus neutralizing antibodiesvirus vaccineblood serumimmunity |
| spellingShingle | A. V. Konstantinov S. K. Starov V. I. Diev N. V. Moroz E. V. Kurnenkova D. K. Basova A. V. Kononov K. Yu. Fedoseyev V. P. Melnikov ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS Ветеринария сегодня оспа овец оспа коз чума мелких жвачных овцы козы вируснейтрализующие антитела вирусвакцина сыворотка крови иммунитет sheep pox goat pox peste des petits rum^nts sheep goats virus neutralizing antibodies virus vaccine blood serum immunity |
| title | ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS |
| title_full | ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS |
| title_fullStr | ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS |
| title_full_unstemmed | ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS |
| title_short | ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS |
| title_sort | antigenic and protective properties of associated virus vaccine against sheep pox goat pox and peste des petits ruminants |
| topic | оспа овец оспа коз чума мелких жвачных овцы козы вируснейтрализующие антитела вирусвакцина сыворотка крови иммунитет sheep pox goat pox peste des petits rum^nts sheep goats virus neutralizing antibodies virus vaccine blood serum immunity |
| url | https://veterinary.arriah.ru/jour/article/view/316 |
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