A central role for TOR signalling in a yeast model for juvenile CLN3 disease
Yeasts provide an excellent genetically tractable eukaryotic system for investigating the function of genes in their biological context, and are especially relevant for those conserved genes that cause disease. We study the role of btn1, the orthologue of a human gene that underlies a...
Saved in:
| Main Authors: | Michael E. Bond, Rachel Brown, Charalampos Rallis, Jürg Bähler, Sara E. Mole |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2015-11-01
|
| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/a-central-role-for-tor-signalling-in-a-yeast-model-for-juvenile-cln3-disease/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evidence of the impact of CLN2 and CLN3 Batten disease on families in the United Kingdom
by: Sara E. Mole, et al.
Published: (2025-05-01) -
Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep
by: Samantha J. Murray, et al.
Published: (2025-04-01) -
The Batten disease gene Cln3 is required for the activation of intestinal stem cell during regeneration via JAK/STAT signaling in Drosophila
by: Zihua Yu, et al.
Published: (2025-01-01) -
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
by: Chiara Soldati, et al.
Published: (2021-08-01) -
Maculopathy and adult‐onset ataxia in patients with biallelic MFSD8 variants
by: Sigurd Dobloug, et al.
Published: (2024-08-01)