Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy
CANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. The disorder results in significant morbidity but is poorly understood and often misdiagnosed. We describe a unique case of CANOMAD, associated with in...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/170543 |
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| _version_ | 1832562996854915072 |
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| author | Kate Johnson Ashish Malkan Mohamed Shaffi |
| author_facet | Kate Johnson Ashish Malkan Mohamed Shaffi |
| author_sort | Kate Johnson |
| collection | DOAJ |
| description | CANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. The disorder results in significant morbidity but is poorly understood and often misdiagnosed. We describe a unique case of CANOMAD, associated with involuntary movements of the face; patient reported exacerbations with citrus and chocolate and respiratory muscle weakness. Our patient was initially misdiagnosed with Miller Fisher Syndrome, highlighting the need for vigilance should neurological symptoms recur in patients initially diagnosed with a Guillain Barre variant. Moreover, the optimal treatment is unknown. This patient responded remarkably to intravenous immunoglobulin and has been maintained on this treatment, without further exacerbations. |
| format | Article |
| id | doaj-art-0e3405cb74114f649196ac668a8a34ae |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-0e3405cb74114f649196ac668a8a34ae2025-02-03T01:21:13ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/170543170543Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG TherapyKate Johnson0Ashish Malkan1Mohamed Shaffi2Department of Neurology, Nepean Hospital, Derby Street, Kingswood, NSW, AustraliaDepartment of Neurology, Nepean Hospital, Derby Street, Kingswood, NSW, AustraliaDepartment of Neurology, Nepean Hospital, Derby Street, Kingswood, NSW, AustraliaCANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. The disorder results in significant morbidity but is poorly understood and often misdiagnosed. We describe a unique case of CANOMAD, associated with involuntary movements of the face; patient reported exacerbations with citrus and chocolate and respiratory muscle weakness. Our patient was initially misdiagnosed with Miller Fisher Syndrome, highlighting the need for vigilance should neurological symptoms recur in patients initially diagnosed with a Guillain Barre variant. Moreover, the optimal treatment is unknown. This patient responded remarkably to intravenous immunoglobulin and has been maintained on this treatment, without further exacerbations.http://dx.doi.org/10.1155/2015/170543 |
| spellingShingle | Kate Johnson Ashish Malkan Mohamed Shaffi Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy Case Reports in Medicine |
| title | Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy |
| title_full | Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy |
| title_fullStr | Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy |
| title_full_unstemmed | Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy |
| title_short | Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy |
| title_sort | facial involuntary movements and respiratory failure in canomad responsive to ivig therapy |
| url | http://dx.doi.org/10.1155/2015/170543 |
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