A highly neutralizing human monoclonal antibody targeting a novel linear epitope on staphylococcal enterotoxin B

A highly neutralizing human monoclonal antibody targeting a novel linear epitope on staphylococcal enterotoxin B

Staphylococcal Enterotoxin B (SEB), produced by Staphylococcus aureus (S. aureus), is a powerful superantigen that induces severe immune disruption and toxic shock syndrome (TSS) upon binding to MHC-II and TCR. Despite its significant impact on the pathogenesis of S. aureus, there are currently no s...

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Bibliographic Details
Main Authors: Hongyin Fan, Liqun Zhao, Weiwei Wang, Feng Yu, Haiming Jing, Yun Yang, Xiaoli Zhang, Zhuo Zhao, Qiang Gou, Weijun Zhang, Quanming Zou, Jinyong Zhang, Hao Zeng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Staphylococcus aureus
enterotoxin B
monoclonal antibody
structure
neutralizing activity
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2360338
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