Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol

Introduction The French emergency department (ED) surveillance network OSCOUR transmits data on ED visits to Santé publique France (the national public health agency). As these data are collected daily and are almost exhaustive at a national level, it would seem relevant to use them for national epi...

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Main Authors: Nozar Aghakhani, Fleur Lorton, Louis-Marie Paget, Anne Gallay, Nathalie Beltzer, Cécile Forgeot, Maurice Raphael
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/12/e059961.full
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author Nozar Aghakhani
Fleur Lorton
Louis-Marie Paget
Anne Gallay
Nathalie Beltzer
Cécile Forgeot
Maurice Raphael
author_facet Nozar Aghakhani
Fleur Lorton
Louis-Marie Paget
Anne Gallay
Nathalie Beltzer
Cécile Forgeot
Maurice Raphael
author_sort Nozar Aghakhani
collection DOAJ
description Introduction The French emergency department (ED) surveillance network OSCOUR transmits data on ED visits to Santé publique France (the national public health agency). As these data are collected daily and are almost exhaustive at a national level, it would seem relevant to use them for national epidemiological surveillance of mild traumatic brain injury (mTBI). This article presents the protocol of a planned study to validate algorithms for identifying mTBI in the OSCOUR database. Algorithms to be tested will be based on International Classification of Diseases (ICD)-10 codes.Methods and analysis We will perform a multicentre validation study of algorithms for identifying mTBI in OSCOUR. Different combinations of ICD-10 codes will be used to identify cases of mTBI in the OSCOUR database. A random sample of mTBI cases and non-cases will be selected from four EDs. Medical charts will serve as the reference standard to validate the algorithms. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the different algorithms, as well as their 95% CIs, will be calculated and compared.Ethics and dissemination The ethics committee of the French National Data Protection Authority (CNIL) approved this study (n° 921152, 1 August 2021). Results will be submitted to national and international peer-reviewed journals and presented at conferences dedicated to trauma and to methodologies for the construction and validation of algorithms.
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spelling doaj-art-0e1cbb472c2b4420baf0e68b96f4404c2025-08-20T02:57:13ZengBMJ Publishing GroupBMJ Open2044-60552022-12-01121210.1136/bmjopen-2021-059961Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocolNozar Aghakhani0Fleur Lorton1Louis-Marie Paget2Anne Gallay3Nathalie Beltzer4Cécile Forgeot5Maurice Raphael63 Neurosurgery, Hôpital Bicêtre, Le Kremlin-Bicêtre, France1 Nantes Université, CHU Nantes, INSERM, Department of Paediatric Emergency, CIC 1413, F-44000 Nantes, FranceDirection des maladies non transmissibles et traumatismes, Santé publique France, Saint-Maurice, Île-de-France, FranceDirection des maladies non transmissibles et traumatismes, Santé publique France, Saint-Maurice, Île-de-France, FranceDirection des maladies non transmissibles et traumatismes, Santé publique France, Saint-Maurice, Île-de-France, FranceDirection Appui, Traitements et Analyses de données, Santé publique France, Saint-Maurice, Île-de-France, FranceUrgences Hirslanden, Lausanne, SwitzerlandIntroduction The French emergency department (ED) surveillance network OSCOUR transmits data on ED visits to Santé publique France (the national public health agency). As these data are collected daily and are almost exhaustive at a national level, it would seem relevant to use them for national epidemiological surveillance of mild traumatic brain injury (mTBI). This article presents the protocol of a planned study to validate algorithms for identifying mTBI in the OSCOUR database. Algorithms to be tested will be based on International Classification of Diseases (ICD)-10 codes.Methods and analysis We will perform a multicentre validation study of algorithms for identifying mTBI in OSCOUR. Different combinations of ICD-10 codes will be used to identify cases of mTBI in the OSCOUR database. A random sample of mTBI cases and non-cases will be selected from four EDs. Medical charts will serve as the reference standard to validate the algorithms. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the different algorithms, as well as their 95% CIs, will be calculated and compared.Ethics and dissemination The ethics committee of the French National Data Protection Authority (CNIL) approved this study (n° 921152, 1 August 2021). Results will be submitted to national and international peer-reviewed journals and presented at conferences dedicated to trauma and to methodologies for the construction and validation of algorithms.https://bmjopen.bmj.com/content/12/12/e059961.full
spellingShingle Nozar Aghakhani
Fleur Lorton
Louis-Marie Paget
Anne Gallay
Nathalie Beltzer
Cécile Forgeot
Maurice Raphael
Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
BMJ Open
title Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
title_full Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
title_fullStr Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
title_full_unstemmed Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
title_short Validity of algorithms for identifying mild traumatic brain injury in the French national emergency department database OSCOUR: a retrospective multicentre validation study protocol
title_sort validity of algorithms for identifying mild traumatic brain injury in the french national emergency department database oscour a retrospective multicentre validation study protocol
url https://bmjopen.bmj.com/content/12/12/e059961.full
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