Desensitization of delayed-type hypersensitivity in mice: suppressive environment
The systemic injection of high doses of antigen into a preimmunized animal results in transient unresponsiveness of cell-mediated immune responses. This phenomenon is known as desensitization. Serum interleukin 2 (IL-2) activity was found transiently in desensitized mice at 3 h after the antigen cha...
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Main Authors: | Takashi Katsura, Kazuo Kobayashi, Michio Hosaka, Sachiko Sugihara, Tsuyoshi Kasama, Keita Kasahara, Stanley Cohen, Takeshi Yoshida |
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Format: | Article |
Language: | English |
Published: |
Wiley
1993-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935193000274 |
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