A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeutic Translation

A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeutic Translation

<b>Background:</b> Autism spectrum disorder (ASD) is increasingly linked to systemic metabolic dysfunction, potentially influenced by gut–brain axis dysregulation, but the underlying mechanisms remain unclear. <b>Methods:</b> We developed Personalized Metabolic Margin Mapping...

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Bibliographic Details
Main Author: Albion Dervishi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Metabolites
Subjects:
autism spectrum disorder (ASD)
systems biology
mitochondrial dysfunction
SLC5A6
SLC19A2
biotin
Online Access:https://www.mdpi.com/2218-1989/15/6/399
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