Neoadjuvant chemotherapy response in androgen receptor-positive triple-negative breast cancer: potential predictive biomarkers and genetic alterations

Neoadjuvant chemotherapy response in androgen receptor-positive triple-negative breast cancer: potential predictive biomarkers and genetic alterations

Abstract Background The aim of the present study was to investigate whether the androgen receptor (AR) status affects the efficacy of neoadjuvant chemotherapy (NACT) in triple negative breast cancer (TNBC) patients, and to elucidate the predictive biomarkers and mutations associated with pathologica...

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Bibliographic Details
Main Authors: Ming Li, Shuling Zhou, Hong Lv, Mengyuan Cai, Ruohong Shui, Wentao Yang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Breast Cancer Research
Subjects:
Androgen receptor
Neoadjuvant chemotherapy
Predictive biomarkers
Genetic alterations
Online Access:https://doi.org/10.1186/s13058-025-01994-y
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