Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats
Acne vulgaris is an inflammatory disorder of the pilosebaceous unit, characterized by lesions such as comedones, papules, pustules, nodules, and cysts. This study aimed to assess the effectiveness of Andaliman Extract Nanoemulgel (Zanthoxylum Acanthopodium DC) in treating acne lesions in male Wistar...
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| Language: | Indonesian |
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Poltekkes Kemenkes Yogyakarta
2024-12-01
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| Series: | Jurnal Teknologi Laboratorium |
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| Online Access: | https://teknolabjournal.com/index.php/Jtl/article/view/501 |
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| author | Micella Tanessa Chrismis Novalinda Ginting Linda Chiuman Masdalena Mangatas Halomoan Parluhutan Hutagalung |
| author_facet | Micella Tanessa Chrismis Novalinda Ginting Linda Chiuman Masdalena Mangatas Halomoan Parluhutan Hutagalung |
| author_sort | Micella Tanessa |
| collection | DOAJ |
| description | Acne vulgaris is an inflammatory disorder of the pilosebaceous unit, characterized by lesions such as comedones, papules, pustules, nodules, and cysts. This study aimed to assess the effectiveness of Andaliman Extract Nanoemulgel (Zanthoxylum Acanthopodium DC) in treating acne lesions in male Wistar rats (Rattus Novergicus) induced with Propionibacterium acnes. This experimental involved 30 male Wistar rats aged 6-8 weeks, weighing 150-200 grams, divided into 6 groups: 1) normal, 2) negative control (P. acnes induction and base gel), 3) positive control (P. acnes induction and Mediklin TR gel), 4) Treatment 1 (P. acnes induction and 2% Nanoemulgel), 5) Treatment 2 (P. acnes induction and 3.5% Nanoemulgel), and 6) Treatment 3 (P. acnes induction and 5% Nanoemulgel). Nanoemulsion application was carried out for 10 days to evaluate the healing of acne lesions on the skin of Wistar rats. Results showed that Andaliman Extract Nanoemulgel effectively healed lesions caused by Propionibacterium acnes. In conclusion, Nanoemulgel with Andaliman fruit extract at concentrations of 2% and 5% demonstrated the highest effectiveness in anti-acne treatment. |
| format | Article |
| id | doaj-art-0e06fbf2dbbe49699e37192039b61080 |
| institution | Kabale University |
| issn | 2338-5634 2580-0191 |
| language | Indonesian |
| publishDate | 2024-12-01 |
| publisher | Poltekkes Kemenkes Yogyakarta |
| record_format | Article |
| series | Jurnal Teknologi Laboratorium |
| spelling | doaj-art-0e06fbf2dbbe49699e37192039b610802025-01-03T15:40:12ZindPoltekkes Kemenkes YogyakartaJurnal Teknologi Laboratorium2338-56342580-01912024-12-0113212613410.29238/teknolabjournal.v13i2.501453Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar ratsMicella Tanessa0Chrismis Novalinda GintingLinda ChiumanMasdalenaMangatas Halomoan Parluhutan Hutagalung-Acne vulgaris is an inflammatory disorder of the pilosebaceous unit, characterized by lesions such as comedones, papules, pustules, nodules, and cysts. This study aimed to assess the effectiveness of Andaliman Extract Nanoemulgel (Zanthoxylum Acanthopodium DC) in treating acne lesions in male Wistar rats (Rattus Novergicus) induced with Propionibacterium acnes. This experimental involved 30 male Wistar rats aged 6-8 weeks, weighing 150-200 grams, divided into 6 groups: 1) normal, 2) negative control (P. acnes induction and base gel), 3) positive control (P. acnes induction and Mediklin TR gel), 4) Treatment 1 (P. acnes induction and 2% Nanoemulgel), 5) Treatment 2 (P. acnes induction and 3.5% Nanoemulgel), and 6) Treatment 3 (P. acnes induction and 5% Nanoemulgel). Nanoemulsion application was carried out for 10 days to evaluate the healing of acne lesions on the skin of Wistar rats. Results showed that Andaliman Extract Nanoemulgel effectively healed lesions caused by Propionibacterium acnes. In conclusion, Nanoemulgel with Andaliman fruit extract at concentrations of 2% and 5% demonstrated the highest effectiveness in anti-acne treatment.https://teknolabjournal.com/index.php/Jtl/article/view/501acne vulgarisnanoemulgel andaliman extractpropionibacterium acnes |
| spellingShingle | Micella Tanessa Chrismis Novalinda Ginting Linda Chiuman Masdalena Mangatas Halomoan Parluhutan Hutagalung Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats Jurnal Teknologi Laboratorium acne vulgaris nanoemulgel andaliman extract propionibacterium acnes |
| title | Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats |
| title_full | Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats |
| title_fullStr | Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats |
| title_full_unstemmed | Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats |
| title_short | Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats |
| title_sort | evaluation of the anti acne effectiveness of andaliman zanthoxylum acanthopodium dc nanoemulgel in propionibacterium acnes induced male wistar rats |
| topic | acne vulgaris nanoemulgel andaliman extract propionibacterium acnes |
| url | https://teknolabjournal.com/index.php/Jtl/article/view/501 |
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