A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics
Introduction: Capnocytophaga canimorsus is a Gram-negative bacterium found in the oral flora of dogs and cats, transmitted to humans through bites, licks, or scratches. Infections can lead to severe manifestations, including meningitis, particularly in immunocompromised individuals. Case Presentatio...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2024-10-01
|
| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | https://beta.karger.com/Article/FullText/541631 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850285091678322688 |
|---|---|
| author | Adrienne Elisabeth van der Hoeven Josephus Johannes Kerremans Tjerk Joppe Lagrand |
| author_facet | Adrienne Elisabeth van der Hoeven Josephus Johannes Kerremans Tjerk Joppe Lagrand |
| author_sort | Adrienne Elisabeth van der Hoeven |
| collection | DOAJ |
| description | Introduction: Capnocytophaga canimorsus is a Gram-negative bacterium found in the oral flora of dogs and cats, transmitted to humans through bites, licks, or scratches. Infections can lead to severe manifestations, including meningitis, particularly in immunocompromised individuals. Case Presentation: A 46-year-old immunocompetent man presented with somnolence, headache, and fever after being licked by his dog. Neurological examination revealed signs of meningeal irritation, and cerebrospinal fluid analysis showed an elevated white cell count and protein levels consistent with bacterial meningitis. Treatment followed Dutch guidelines with amoxicillin, ceftriaxone, and dexamethasone, resulting in rapid clinical improvement. Microbiological confirmation of C. canimorsus followed later. The patient was treated with antibiotics for the duration of 1 week and remained symptom-free after being discharged. Conclusion: C. canimorsus meningitis, although rare, poses diagnostic challenges due to its variable presentation and slow growth in culture. Empirical therapy guided by susceptibility testing contributes to favorable outcomes. This case underscores the importance of considering a C. canimorsus infection in patients with animal exposure and of taking diagnostic findings, precedent, and clinical response into account when determining the treatment duration. |
| format | Article |
| id | doaj-art-0df3b830a50f45d7a6387cb7b5a617ec |
| institution | OA Journals |
| issn | 1662-680X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj-art-0df3b830a50f45d7a6387cb7b5a617ec2025-08-20T01:47:23ZengKarger PublishersCase Reports in Neurology1662-680X2024-10-0116126927310.1159/000541631541631A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of AntibioticsAdrienne Elisabeth van der Hoeven0Josephus Johannes Kerremans1Tjerk Joppe Lagrand2Department of Neurology, Alrijne Ziekenhuis, Leiderdorp, The NetherlandsDepartment of Medical Microbiology, Alrijne Ziekenhuis, Leiderdorp, The NetherlandsDepartment of Neurology, Alrijne Ziekenhuis, Leiderdorp, The NetherlandsIntroduction: Capnocytophaga canimorsus is a Gram-negative bacterium found in the oral flora of dogs and cats, transmitted to humans through bites, licks, or scratches. Infections can lead to severe manifestations, including meningitis, particularly in immunocompromised individuals. Case Presentation: A 46-year-old immunocompetent man presented with somnolence, headache, and fever after being licked by his dog. Neurological examination revealed signs of meningeal irritation, and cerebrospinal fluid analysis showed an elevated white cell count and protein levels consistent with bacterial meningitis. Treatment followed Dutch guidelines with amoxicillin, ceftriaxone, and dexamethasone, resulting in rapid clinical improvement. Microbiological confirmation of C. canimorsus followed later. The patient was treated with antibiotics for the duration of 1 week and remained symptom-free after being discharged. Conclusion: C. canimorsus meningitis, although rare, poses diagnostic challenges due to its variable presentation and slow growth in culture. Empirical therapy guided by susceptibility testing contributes to favorable outcomes. This case underscores the importance of considering a C. canimorsus infection in patients with animal exposure and of taking diagnostic findings, precedent, and clinical response into account when determining the treatment duration.https://beta.karger.com/Article/FullText/541631capnocytophaga canimorsusbacterial meningitiszoonosisantibiotic treatmentcase report |
| spellingShingle | Adrienne Elisabeth van der Hoeven Josephus Johannes Kerremans Tjerk Joppe Lagrand A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics Case Reports in Neurology capnocytophaga canimorsus bacterial meningitis zoonosis antibiotic treatment case report |
| title | A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics |
| title_full | A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics |
| title_fullStr | A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics |
| title_full_unstemmed | A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics |
| title_short | A Rare Case of Capnocytophaga canimorsus Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics |
| title_sort | rare case of capnocytophaga canimorsus meningitis in an immunocompetent patient a successful outcome with a short course of antibiotics |
| topic | capnocytophaga canimorsus bacterial meningitis zoonosis antibiotic treatment case report |
| url | https://beta.karger.com/Article/FullText/541631 |
| work_keys_str_mv | AT adrienneelisabethvanderhoeven ararecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics AT josephusjohanneskerremans ararecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics AT tjerkjoppelagrand ararecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics AT adrienneelisabethvanderhoeven rarecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics AT josephusjohanneskerremans rarecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics AT tjerkjoppelagrand rarecaseofcapnocytophagacanimorsusmeningitisinanimmunocompetentpatientasuccessfuloutcomewithashortcourseofantibiotics |