Adaptive Behavior in Young Children with Neurofibromatosis Type 1
Neurofibromatosis-1 is the most common single gene disorder affecting 1 in 3000. In children, it is associated not only with physical features but also with attention and learning problems. Research has identified a downward shift in intellectual functioning as well, but to date, there are no publis...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2013/690432 |
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| author | Bonita P. Klein-Tasman Alina M. Colon Natalie Brei Faye van der Fluit Christina L. Casnar Kelly M. Janke Donald Basel Dawn H. Siegel Jasmine A. Walker |
| author_facet | Bonita P. Klein-Tasman Alina M. Colon Natalie Brei Faye van der Fluit Christina L. Casnar Kelly M. Janke Donald Basel Dawn H. Siegel Jasmine A. Walker |
| author_sort | Bonita P. Klein-Tasman |
| collection | DOAJ |
| description | Neurofibromatosis-1 is the most common single gene disorder affecting 1 in 3000. In children, it is associated not only with physical features but also with attention and learning problems. Research has identified a downward shift in intellectual functioning as well, but to date, there are no published studies about the everyday adaptive behavior of children with NF1. In this study, parental reports of adaptive behavior of 61 children with NF1 ages 3 through 8 were compared to an unaffected contrast group (n=55) that comprised siblings and community members. Significant group differences in adaptive skills were evident and were largely related to group differences in intellectual functioning. In a subsample of children with average-range intellectual functioning, group differences in parent-reported motor skills were apparent even after controlling statistically for group differences in intellectual functioning. The implications of the findings for the care of children with NF1 are discussed. |
| format | Article |
| id | doaj-art-0dedb7fcd5f040218b665dc25a699e3f |
| institution | OA Journals |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-0dedb7fcd5f040218b665dc25a699e3f2025-08-20T02:02:30ZengWileyInternational Journal of Pediatrics1687-97401687-97592013-01-01201310.1155/2013/690432690432Adaptive Behavior in Young Children with Neurofibromatosis Type 1Bonita P. Klein-Tasman0Alina M. Colon1Natalie Brei2Faye van der Fluit3Christina L. Casnar4Kelly M. Janke5Donald Basel6Dawn H. Siegel7Jasmine A. Walker8University of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USAMedical College of Wisconsin, Milwaukee, WI 53226, USAMedical College of Wisconsin, Milwaukee, WI 53226, USAUniversity of Wisconsin - Milwaukee, Milwaukee, WI 53201, USANeurofibromatosis-1 is the most common single gene disorder affecting 1 in 3000. In children, it is associated not only with physical features but also with attention and learning problems. Research has identified a downward shift in intellectual functioning as well, but to date, there are no published studies about the everyday adaptive behavior of children with NF1. In this study, parental reports of adaptive behavior of 61 children with NF1 ages 3 through 8 were compared to an unaffected contrast group (n=55) that comprised siblings and community members. Significant group differences in adaptive skills were evident and were largely related to group differences in intellectual functioning. In a subsample of children with average-range intellectual functioning, group differences in parent-reported motor skills were apparent even after controlling statistically for group differences in intellectual functioning. The implications of the findings for the care of children with NF1 are discussed.http://dx.doi.org/10.1155/2013/690432 |
| spellingShingle | Bonita P. Klein-Tasman Alina M. Colon Natalie Brei Faye van der Fluit Christina L. Casnar Kelly M. Janke Donald Basel Dawn H. Siegel Jasmine A. Walker Adaptive Behavior in Young Children with Neurofibromatosis Type 1 International Journal of Pediatrics |
| title | Adaptive Behavior in Young Children with Neurofibromatosis Type 1 |
| title_full | Adaptive Behavior in Young Children with Neurofibromatosis Type 1 |
| title_fullStr | Adaptive Behavior in Young Children with Neurofibromatosis Type 1 |
| title_full_unstemmed | Adaptive Behavior in Young Children with Neurofibromatosis Type 1 |
| title_short | Adaptive Behavior in Young Children with Neurofibromatosis Type 1 |
| title_sort | adaptive behavior in young children with neurofibromatosis type 1 |
| url | http://dx.doi.org/10.1155/2013/690432 |
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