Radiation induced dermatitis by increasing triglyceride levels to induce autophagy and inhibit the PI3K/Akt/mTOR signaling pathway

Radiation induced dermatitis by increasing triglyceride levels to induce autophagy and inhibit the PI3K/Akt/mTOR signaling pathway

Abstract Background Radiodermatitis (RD) is the primary acute adverse effect experienced by patients receiving radiotherapy (RT) for head and neck cancer (HNC). This study aimed to investigate the correlation between triglyceride (TG) levels and the severity of RD, as well as the underlying mechanis...

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Bibliographic Details
Main Authors: Yafang Hong, Hongdan Guan, Yunhao Chen, Yao Wang, Junjian Lin, Ying Wang, Yang Zhang, Rong Zheng, Xingchen Ding, Zihan Zhou, Benhua Xu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Lipids in Health and Disease
Subjects:
Head and neck cancer
Radiodermatitis
Triglyceride
Autophagy
PI3K/Akt/mTOR pathway
Online Access:https://doi.org/10.1186/s12944-025-02553-2
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