Use of prototype bi‐nasal prongs for noninvasive ventilation in foals

Abstract Background Noninvasive ventilation (NIV) provides effective respiratory support in foals, but face masks are poorly tolerated and associated with hypercapnia. Bi‐nasal prongs might be a more effective device interface in foals. Objectives To compare bi‐nasal prongs and masks for NIV in foal...

Full description

Saved in:
Bibliographic Details
Main Authors: Sharanne L. Raidal, Michael vanDiggelen, Chee Sum M. Catanchin, Heidi S. Lehmann, Chris T. Quinn
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Veterinary Internal Medicine
Subjects:
Online Access:https://doi.org/10.1111/jvim.17170
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850159094003924992
author Sharanne L. Raidal
Michael vanDiggelen
Chee Sum M. Catanchin
Heidi S. Lehmann
Chris T. Quinn
author_facet Sharanne L. Raidal
Michael vanDiggelen
Chee Sum M. Catanchin
Heidi S. Lehmann
Chris T. Quinn
author_sort Sharanne L. Raidal
collection DOAJ
description Abstract Background Noninvasive ventilation (NIV) provides effective respiratory support in foals, but face masks are poorly tolerated and associated with hypercapnia. Bi‐nasal prongs might be a more effective device interface in foals. Objectives To compare bi‐nasal prongs and masks for NIV in foals with pharmacologically induced respiratory insufficiency. Animals Six healthy foals. Methods In a randomized cross‐over study, sedated foals received NIV delivered by mask or bi‐nasal prongs, with the treatment repeated using the alternative device interface after a 3‐day rest period. After periods of spontaneous ventilation through the allocated interface, with and without supplementary O2 (T2‐T3), foals were subject to 10‐minute treatment periods of NIV at different pressure support (5 or 10 cmH2O) and end‐expiratory pressure settings (5 or 10 cmH2O), with and without supplementary O2 (T4‐T7). Vital signs, arterial blood gases, spirometry, and gas exchange data were measured in the final 2 minutes of each treatment window. Results Bi‐nasal prongs were well tolerated and required less manual positioning or monitoring compared to the mask. Partial pressure of carbon dioxide did not increase during NIV with bi‐nasal prongs and was lower than observed with masks (mean difference, 8.2 mmHg [95% confidence interval, 4.1‐12.2 mmHg] at T6). Oxygenation and respiratory mechanics were improved in all foals and not different between device interfaces. Conclusions and Clinical Importance Nasal prongs were well tolerated, had similar effects on respiratory function, and appeared to ameliorate hypercapnia observed previously during NIV in foals.
format Article
id doaj-art-0dd8f483a7fd495bb0dfae8f7ebe3993
institution OA Journals
issn 0891-6640
1939-1676
language English
publishDate 2024-11-01
publisher Wiley
record_format Article
series Journal of Veterinary Internal Medicine
spelling doaj-art-0dd8f483a7fd495bb0dfae8f7ebe39932025-08-20T02:23:40ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762024-11-013863327333610.1111/jvim.17170Use of prototype bi‐nasal prongs for noninvasive ventilation in foalsSharanne L. Raidal0Michael vanDiggelen1Chee Sum M. Catanchin2Heidi S. Lehmann3Chris T. Quinn4Veterinary Clinical Centre, School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University Wagga Wagga New South Wales AustraliaVeterinary Clinical Centre, School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University Wagga Wagga New South Wales AustraliaVeterinary Clinical Centre, School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University Wagga Wagga New South Wales AustraliaVeterinary Clinical Centre, School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University Wagga Wagga New South Wales AustraliaVeterinary Clinical Centre, School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University Wagga Wagga New South Wales AustraliaAbstract Background Noninvasive ventilation (NIV) provides effective respiratory support in foals, but face masks are poorly tolerated and associated with hypercapnia. Bi‐nasal prongs might be a more effective device interface in foals. Objectives To compare bi‐nasal prongs and masks for NIV in foals with pharmacologically induced respiratory insufficiency. Animals Six healthy foals. Methods In a randomized cross‐over study, sedated foals received NIV delivered by mask or bi‐nasal prongs, with the treatment repeated using the alternative device interface after a 3‐day rest period. After periods of spontaneous ventilation through the allocated interface, with and without supplementary O2 (T2‐T3), foals were subject to 10‐minute treatment periods of NIV at different pressure support (5 or 10 cmH2O) and end‐expiratory pressure settings (5 or 10 cmH2O), with and without supplementary O2 (T4‐T7). Vital signs, arterial blood gases, spirometry, and gas exchange data were measured in the final 2 minutes of each treatment window. Results Bi‐nasal prongs were well tolerated and required less manual positioning or monitoring compared to the mask. Partial pressure of carbon dioxide did not increase during NIV with bi‐nasal prongs and was lower than observed with masks (mean difference, 8.2 mmHg [95% confidence interval, 4.1‐12.2 mmHg] at T6). Oxygenation and respiratory mechanics were improved in all foals and not different between device interfaces. Conclusions and Clinical Importance Nasal prongs were well tolerated, had similar effects on respiratory function, and appeared to ameliorate hypercapnia observed previously during NIV in foals.https://doi.org/10.1111/jvim.17170equine critical careequine neonatologyequine respiratory physiologyfoalnoninvasive ventilation (NIV)pressure support ventilation (PSV)
spellingShingle Sharanne L. Raidal
Michael vanDiggelen
Chee Sum M. Catanchin
Heidi S. Lehmann
Chris T. Quinn
Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
Journal of Veterinary Internal Medicine
equine critical care
equine neonatology
equine respiratory physiology
foal
noninvasive ventilation (NIV)
pressure support ventilation (PSV)
title Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
title_full Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
title_fullStr Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
title_full_unstemmed Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
title_short Use of prototype bi‐nasal prongs for noninvasive ventilation in foals
title_sort use of prototype bi nasal prongs for noninvasive ventilation in foals
topic equine critical care
equine neonatology
equine respiratory physiology
foal
noninvasive ventilation (NIV)
pressure support ventilation (PSV)
url https://doi.org/10.1111/jvim.17170
work_keys_str_mv AT sharannelraidal useofprototypebinasalprongsfornoninvasiveventilationinfoals
AT michaelvandiggelen useofprototypebinasalprongsfornoninvasiveventilationinfoals
AT cheesummcatanchin useofprototypebinasalprongsfornoninvasiveventilationinfoals
AT heidislehmann useofprototypebinasalprongsfornoninvasiveventilationinfoals
AT christquinn useofprototypebinasalprongsfornoninvasiveventilationinfoals