Deciphering the structural consequences of R83 and R152 methylation on DNA polymerase β using molecular modeling.

DNA polymerase β, a member of the X-family of DNA polymerases, undergoes complex regulations both in vitro and in vivo through various posttranslational modifications, including phosphorylation and methylation. The impact of these modifications varies depending on the specific amino acid undergoing...

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Bibliographic Details
Main Authors: Amit Srivastava, Haitham Idriss, Gobind Das, Sufian Abedrabbo, Mohd Sahir Shamsir, Dirar Homouz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318614
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