An In‐Silico Study to Identify Relevant Biomarkers in Sepsis Applying Integrated Bulk RNA Sequencing and Single‐Cell RNA Sequencing Analyses

An In‐Silico Study to Identify Relevant Biomarkers in Sepsis Applying Integrated Bulk RNA Sequencing and Single‐Cell RNA Sequencing Analyses

Abstract This study aims to discover sepsis‐related biomarkers via in‐silico analyses. The single‐cell sequencing RNA (sc‐RNA) data and metabolism‐related genes are obtained from public databases and previous studies, respectively. Cell subpopulations are identified and annotated, followed by perfor...

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Bibliographic Details
Main Authors: Qile Ye, Yuhang Dong, Jingting Liang, Jingyao Lv, Rong Tang, Shuai Zhao, Guiying Hou
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Global Challenges
Subjects:
bulk RNA sequencing analysis
cell–cell communication
monocytes
sepsis
single‐cell RNA sequencing analysis
Online Access:https://doi.org/10.1002/gch2.202400321
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