Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review
The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, longitudinal cohort study designed to evaluate environmental, lifestyle, and genetic risk factors as they relate to cardiometabolic and other chronic diseases among Hispanic/Latino populations in the United States. Sin...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | HGG Advances |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666247724001167 |
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| author | Hridya Rao Margaret C. Weiss Jee Young Moon Krista M. Perreira Martha L. Daviglus Robert Kaplan Kari E. North Maria Argos Lindsay Fernández-Rhodes Tamar Sofer |
| author_facet | Hridya Rao Margaret C. Weiss Jee Young Moon Krista M. Perreira Martha L. Daviglus Robert Kaplan Kari E. North Maria Argos Lindsay Fernández-Rhodes Tamar Sofer |
| author_sort | Hridya Rao |
| collection | DOAJ |
| description | The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, longitudinal cohort study designed to evaluate environmental, lifestyle, and genetic risk factors as they relate to cardiometabolic and other chronic diseases among Hispanic/Latino populations in the United States. Since the study’s inception in 2008, as a result of the study’s robust genetic measures, HCHS/SOL has facilitated major contributions to the field of genetic research. This 10-year retrospective review highlights the major findings for genotype-phenotype relationships and advancements in statistical methods owing to the HCHS/SOL. Furthermore, we discuss the ethical and societal challenges of genetic research, especially among Hispanic/Latino adults in the United States. Continued genetic research, ancillary study expansion, and consortia collaboration through HCHS/SOL will further drive knowledge and advancements in human genetics research. |
| format | Article |
| id | doaj-art-0dc731db83fc46dbb04163bd49cbbbbe |
| institution | Kabale University |
| issn | 2666-2477 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | HGG Advances |
| spelling | doaj-art-0dc731db83fc46dbb04163bd49cbbbbe2024-11-20T05:08:17ZengElsevierHGG Advances2666-24772025-01-0161100376Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective reviewHridya Rao0Margaret C. Weiss1Jee Young Moon2Krista M. Perreira3Martha L. Daviglus4Robert Kaplan5Kari E. North6Maria Argos7Lindsay Fernández-Rhodes8Tamar Sofer9Department of Biobehavioral Health, Pennsylvania State University, University Park, PA, USADepartment of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, USADepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USADepartment of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USAInstitute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USADepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USADepartment of Epidemiology, University of North Carolina, Chapel Hill, NC, USADepartment of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, USA; Department of Environmental Health, School of Public Health, Boston University, Boston, MA, USADepartment of Biobehavioral Health, Pennsylvania State University, University Park, PA, USACardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA; Corresponding authorThe Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, longitudinal cohort study designed to evaluate environmental, lifestyle, and genetic risk factors as they relate to cardiometabolic and other chronic diseases among Hispanic/Latino populations in the United States. Since the study’s inception in 2008, as a result of the study’s robust genetic measures, HCHS/SOL has facilitated major contributions to the field of genetic research. This 10-year retrospective review highlights the major findings for genotype-phenotype relationships and advancements in statistical methods owing to the HCHS/SOL. Furthermore, we discuss the ethical and societal challenges of genetic research, especially among Hispanic/Latino adults in the United States. Continued genetic research, ancillary study expansion, and consortia collaboration through HCHS/SOL will further drive knowledge and advancements in human genetics research.http://www.sciencedirect.com/science/article/pii/S2666247724001167 |
| spellingShingle | Hridya Rao Margaret C. Weiss Jee Young Moon Krista M. Perreira Martha L. Daviglus Robert Kaplan Kari E. North Maria Argos Lindsay Fernández-Rhodes Tamar Sofer Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review HGG Advances |
| title | Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review |
| title_full | Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review |
| title_fullStr | Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review |
| title_full_unstemmed | Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review |
| title_short | Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review |
| title_sort | advancements in genetic research by the hispanic community health study study of latinos a 10 year retrospective review |
| url | http://www.sciencedirect.com/science/article/pii/S2666247724001167 |
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