Nonhealing Ulcer: Acroangiodermatitis of Mali
An 18-year-old male presented with a nonhealing wound on left lower limb, pain and swelling over multiple joints, weight loss, and yellowish discoloration of eyes and urine for the past 4 years. On examination, the patient had pallor, icterus, and generalized lymphadenopathy with a nonhealing unheal...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/909383 |
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| author | Neeraj Varyani Anubhav Thukral Nilesh Kumar Kailash Kumar Gupta Ravi Tandon Kamlakar Tripathi |
| author_facet | Neeraj Varyani Anubhav Thukral Nilesh Kumar Kailash Kumar Gupta Ravi Tandon Kamlakar Tripathi |
| author_sort | Neeraj Varyani |
| collection | DOAJ |
| description | An 18-year-old male presented with a nonhealing wound on left lower limb, pain and swelling over multiple joints, weight loss, and yellowish discoloration of eyes and urine for the past 4 years. On examination, the patient had pallor, icterus, and generalized lymphadenopathy with a nonhealing unhealthy ulcer over left medial malleolus. He had deformed joints with hepatomegaly and splenomegaly. His laboratory investigations were positive for antinuclear antibody (ANA) and anticardiolipin antibody (ACLA). Synovial fluid analysis showed inflammatory findings. Biopsy of margin of the ulcer showed findings consistent with Acroangiodermatitis of Mali. The patient was treated with disease-modifying antirheumatic drugs (DMARDs) and aspirin for juvenile idiopathic arthritis and secondary antiphospholipid antibody syndrome (APS), respectively. The ulcer was managed conservatively with systemic antibiotics and topical steroids along with limb elevation and compression elastic stockings. The patient's symptoms improved significantly, and he is in our followup. |
| format | Article |
| id | doaj-art-0dbd656130a64d4db03ee043fc44e698 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-0dbd656130a64d4db03ee043fc44e6982025-08-20T03:54:24ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712011-01-01201110.1155/2011/909383909383Nonhealing Ulcer: Acroangiodermatitis of MaliNeeraj Varyani0Anubhav Thukral1Nilesh Kumar2Kailash Kumar Gupta3Ravi Tandon4Kamlakar Tripathi5Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005, IndiaAn 18-year-old male presented with a nonhealing wound on left lower limb, pain and swelling over multiple joints, weight loss, and yellowish discoloration of eyes and urine for the past 4 years. On examination, the patient had pallor, icterus, and generalized lymphadenopathy with a nonhealing unhealthy ulcer over left medial malleolus. He had deformed joints with hepatomegaly and splenomegaly. His laboratory investigations were positive for antinuclear antibody (ANA) and anticardiolipin antibody (ACLA). Synovial fluid analysis showed inflammatory findings. Biopsy of margin of the ulcer showed findings consistent with Acroangiodermatitis of Mali. The patient was treated with disease-modifying antirheumatic drugs (DMARDs) and aspirin for juvenile idiopathic arthritis and secondary antiphospholipid antibody syndrome (APS), respectively. The ulcer was managed conservatively with systemic antibiotics and topical steroids along with limb elevation and compression elastic stockings. The patient's symptoms improved significantly, and he is in our followup.http://dx.doi.org/10.1155/2011/909383 |
| spellingShingle | Neeraj Varyani Anubhav Thukral Nilesh Kumar Kailash Kumar Gupta Ravi Tandon Kamlakar Tripathi Nonhealing Ulcer: Acroangiodermatitis of Mali Case Reports in Dermatological Medicine |
| title | Nonhealing Ulcer: Acroangiodermatitis of Mali |
| title_full | Nonhealing Ulcer: Acroangiodermatitis of Mali |
| title_fullStr | Nonhealing Ulcer: Acroangiodermatitis of Mali |
| title_full_unstemmed | Nonhealing Ulcer: Acroangiodermatitis of Mali |
| title_short | Nonhealing Ulcer: Acroangiodermatitis of Mali |
| title_sort | nonhealing ulcer acroangiodermatitis of mali |
| url | http://dx.doi.org/10.1155/2011/909383 |
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