SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma

SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma

Solute carrier family 27 member 5 (SLC27A5/FATP5) is a liver-specific metabolic enzyme that plays a crucial role in fatty acid transport and bile acid metabolism. Deficiency of SLC27A5 promotes the progression of hepatocellular carcinoma (HCC) and is strongly associated with a poor prognosis. SLC27A...

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Bibliographic Details
Main Authors: Xin Tang, Junji Tao, Yuanyuan Liu, Deao Gong, Xuefeng Shan, Kai Wang, Ni Tang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-07-01
Series:Genes and Diseases
Subjects:
Alternative polyadenylation
Hepatocellular carcinoma
METTL14
SLC27A5
Stemness
Online Access:http://www.sciencedirect.com/science/article/pii/S235230422400285X
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