Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.

<h4>Background</h4>An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to...

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Main Authors: Paul Walters, Elizabeth A Barley, Anthony Mann, Rachel Phillips, André Tylee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0098342
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author Paul Walters
Elizabeth A Barley
Anthony Mann
Rachel Phillips
André Tylee
author_facet Paul Walters
Elizabeth A Barley
Anthony Mann
Rachel Phillips
André Tylee
author_sort Paul Walters
collection DOAJ
description <h4>Background</h4>An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline.<h4>Method</h4>Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems.<h4>Results</h4>803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98).<h4>Conclusion</h4>Problems living alone, chest pain and disability are important predictors of depression in this population.
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spelling doaj-art-0dae74c95b7940ae82f4e5542f1483252025-08-20T03:11:26ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0196e9834210.1371/journal.pone.0098342Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.Paul WaltersElizabeth A BarleyAnthony MannRachel PhillipsAndré Tylee<h4>Background</h4>An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline.<h4>Method</h4>Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems.<h4>Results</h4>803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98).<h4>Conclusion</h4>Problems living alone, chest pain and disability are important predictors of depression in this population.https://doi.org/10.1371/journal.pone.0098342
spellingShingle Paul Walters
Elizabeth A Barley
Anthony Mann
Rachel Phillips
André Tylee
Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
PLoS ONE
title Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
title_full Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
title_fullStr Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
title_full_unstemmed Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
title_short Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study.
title_sort depression in primary care patients with coronary heart disease baseline findings from the upbeat uk study
url https://doi.org/10.1371/journal.pone.0098342
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AT rachelphillips depressioninprimarycarepatientswithcoronaryheartdiseasebaselinefindingsfromtheupbeatukstudy
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