Regulation of DNA methylation in lesional tissue of children with atopic dermatitis

Regulation of DNA methylation in lesional tissue of children with atopic dermatitis

BackgroundGenetic and epigenetic mechanisms have been shown to play a role in the pathogenesis of atopic dermatitis (AD). However, the role of genes involved in the establishment of DNA methylation has not yet been demonstrated.MethodsA total of 15 pediatric patients with AD and 15 healthy volunteer...

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Bibliographic Details
Main Authors: Demet Kartal, Muhammed Hanefi Dirican, Serpil Taheri, Mehmet Memiş, Eda Öksüm Solak, Salih Levent Cinar, Murat Borlu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Medicine
Subjects:
atopic dermatitis
DNA methylation
TET1-2 and DNMT gene expression
epigenetic
pediatric atopic dermatitis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1531777/full
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